Anti-DLAT monoclonal Antibody

Pyruvate Dehydrogenase E2 antibody

Boster Bio Anti-DLAT monoclonal Antibody catalog # M04469. Tested in WB,ICC,IP applications. This antibody reacts with Human,Mouse.

Product Info Summary

SKU: M04469
Size: 100ul
Reactive Species: Human, Mouse
Host: Mouse
Application: IP, ICC, WB

Product Name

Anti-DLAT monoclonal Antibody

View all Pyruvate Dehydrogenase E2 Antibodies

SKU/Catalog Number

M04469

Size

100ul

Form

Liquid

Description

Boster Bio Anti-DLAT monoclonal Antibody catalog # M04469. Tested in WB,ICC,IP applications. This antibody reacts with Human,Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DLAT monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04469)

Host

Mouse

Contents

Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Monoclonal

Clone Number

AS1A36

Isotype

IgG

Immunogen

Synthesized peptide derived from human Oct-2 (Oct2)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M04469 is reactive to DLAT in Human, Mouse

Applications

M04469 is guaranteed for IP, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

68.997kDa

Background of Pyruvate Dehydrogenase E2

Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000
ICC: 1:300
IP: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For DLAT (Source: Uniprot.org, NCBI)

Gene Name

DLAT

Full Name

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

Weight

68.997kDa

Superfamily

2-oxoacid dehydrogenase family

Alternative Names

70 kDa mitochondrial autoantigen of primary biliary cirrhosis; dihydrolipoamide S-acetyltransferase; DLTA; E2 component of pyruvate dehydrogenase complex; EC 2.3.1; M2 antigen complex 70 kDa subunit; PBC; PDC-E2EC 2.3.1.12; PDCE2mitochondrial DLAT DLTA, E2, PBC, PDC-E2, PDCE2 dihydrolipoamide S-acetyltransferase dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial|70 kDa mitochondrial autoantigen of primary biliary cirrhosis|E2 component of pyruvate dehydrogenase complex|M2 antigen complex 70 kDa subunit|dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex|pyruvate dehydrogenase complex component E2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DLAT, check out the DLAT Infographic

DLAT infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DLAT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M04469-100ul

100ul

$482

Free Secondary Antibody

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M04469
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$482.00

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