Product Info Summary
SKU: | M04469 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Mouse |
Application: | IP, ICC, WB |
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Product info
Product Name
Anti-DLAT monoclonal Antibody
View all Pyruvate Dehydrogenase E2 Antibodies
SKU/Catalog Number
M04469
Size
100ul
Form
Liquid
Description
Boster Bio Anti-DLAT monoclonal Antibody catalog # M04469. Tested in WB,ICC,IP applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-DLAT monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04469)
Host
Mouse
Contents
Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Monoclonal
Clone Number
AS1A36
Isotype
IgG
Immunogen
Synthesized peptide derived from human Oct-2 (Oct2)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
M04469 is reactive to DLAT in Human, Mouse
Applications
M04469 is guaranteed for IP, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
68.997kDa
Background of Pyruvate Dehydrogenase E2
Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
ICC: 1:300
IP: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For DLAT (Source: Uniprot.org, NCBI)
Gene Name
DLAT
Full Name
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Weight
68.997kDa
Superfamily
2-oxoacid dehydrogenase family
Alternative Names
70 kDa mitochondrial autoantigen of primary biliary cirrhosis; dihydrolipoamide S-acetyltransferase; DLTA; E2 component of pyruvate dehydrogenase complex; EC 2.3.1; M2 antigen complex 70 kDa subunit; PBC; PDC-E2EC 2.3.1.12; PDCE2mitochondrial DLAT DLTA, E2, PBC, PDC-E2, PDCE2 dihydrolipoamide S-acetyltransferase dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial|70 kDa mitochondrial autoantigen of primary biliary cirrhosis|E2 component of pyruvate dehydrogenase complex|M2 antigen complex 70 kDa subunit|dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex|pyruvate dehydrogenase complex component E2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DLAT, check out the DLAT Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DLAT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DLAT monoclonal Antibody (M04469)
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No publications found for M04469
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Customer Reviews
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