Anti-DNA Ligase III LIG3 Antibody

Product Name

Anti-DNA Ligase III LIG3 Antibody

View all DNA Ligase III Antibodies

SKU/Catalog Number

A02741

Size

100μl

Form

Liquid

Description

Boster Bio Anti-DNA Ligase III LIG3 Antibody catalog # A02741. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DNA Ligase III LIG3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02741)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

4H4

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human DNA Ligase III. at AA rangle: 110-190

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02741 is reactive to LIG3 in Human, Mouse, Rat

Applications

A02741 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

112.907kDa

Background of DNA Ligase III

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Emamian ES, et al. (2004) J Neurosci. 24(7): 1561-4
Palmer, C.L. et al. (2005) Pharmacol. Rev. 57, 253-277.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of MCF7 cells using DNA Ligase III Polyclonal antibody.

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Western Blot (WB) analysis of specific cells using DNA Ligase III Polyclonal antibody.

Gene/Protein Information For LIG3 (Source: Uniprot.org, NCBI)

Alternative Names

DNA ligase 3; DNA ligase III; EC 6.5.1.1; LIG2; ligase II, DNA, ATP-dependent; ligase III, DNA, ATP-dependent; Polydeoxyribonucleotide synthase [ATP] 3 LIG3 LIG2alpha, LIG3 DNA ligase 3 DNA ligase 3|ligase II, DNA, ATP-dependent|ligase III, DNA, ATP-dependent|polydeoxyribonucleotide synthase [ATP] 3

For more info on LIG3, check out the LIG3 Infographic

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In this infographic, you will see the following information for LIG3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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