Anti-Ephrin type-A receptor 7 EphA7 Monoclonal Antibody

Product Name

Anti-Ephrin type-A receptor 7 EphA7 Monoclonal Antibody

View all EPHA7 Antibodies

SKU/Catalog Number

M03943

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Ephrin type-A receptor 7 EphA7 Monoclonal Antibody catalog # M03943. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Ephrin type-A receptor 7 EphA7 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03943)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

6C8G7

Isotype

IgG

Immunogen

Purified recombinant fragment of EphA7 (aa27-210) expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M03943 is reactive to EPHA7 in Human

Applications

M03943 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

112.097kDa

Background of EPHA7

Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000

Validation Images & Assay Conditions

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Figure 2. Immunohistochemistry validation of EPHA7 using Anti-Ephrin type-A receptor 7 EphA7 Monoclonal Antibody (M03943).

Immunohistochemistry (IHC) analysis of paraffin-embedded Human Breast tissues with AEC staining using EphA7 Monoclonal Antibody.
For more protocol information of IHC

Click image to see more details

Figure 1. Western blotting validation for Anti-Ephrin type-A receptor 7 EphA7 Monoclonal Antibody M03943

Western Blot (WB) analysis using EphA7 Monoclonal Antibody against truncated GST-EphA7 recombinant protein (1) and truncated EphA7 (aa25-556)-hIgGFc transfected CHOK1 cell lysate (2).
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For EPHA7 (Source: Uniprot.org, NCBI)

Alternative Names

Cek11; Ebk; EC 2.7.10; EC 2.7.10.1; Ehk3; EHK-3; EK11; EPH homology kinase 3; Eph homology kinase-3; EPH receptor A7; EphA7; EPH-like kinase 11; ephrin type-A receptor 7; Hek11; Mdk1; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3 EPHA7 EHK-3, EHK3, EK11, HEK11 EPH receptor A7 ephrin type-A receptor 7|EPH homology kinase 3|EPH-like kinase 11|Eph homology kinase-3|receptor protein-tyrosine kinase HEK11|tyrosine-protein kinase receptor EHK-3

For more info on EPHA7, check out the EPHA7 Infographic

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In this infographic, you will see the following information for EPHA7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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