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Product Info Summary
| SKU: | A17028 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-FAM59B GAREM2 Antibody
SKU/Catalog Number
A17028
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-FAM59B GAREM2 Antibody (Catalog # A17028). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
FAM59B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-FAM59B GAREM2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A17028)
Host
Rabbit
Contents
FAM59B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
FAM59B antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAM59B. The immunogen is located within amino acids 600 - 650 of FAM59B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
OGFOD2 antibody is predicted to not cross-react with other TPA1 protein family members. At least three isoforms are known to exist; this antibody will only detect the two larger isoforms.
Reactive Species
A17028 is reactive to GAREM2 in Human, Mouse, Rat
Applications
A17028 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
92.882kDa
Background of FAM59B
FAM59B is related to the FAM59A protein (also known as GAREM). While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FAM59B antibody can be used for detection of FAM59B by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of FAM59B in SK-N-SH cell lysate with FAM59B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of FAM59B in human brain tissue with FAM59B antibody at 5 μg/mL.
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Immunofluorescence of FAM59B in Human Brain cells with FAM59B antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For GAREM2 (Source: Uniprot.org, NCBI)
Gene Name
GAREM2
Full Name
GRB2-associated and regulator of MAPK protein 2
Weight
92.882kDa
Superfamily
GAREM family
Alternative Names
FAM59B; Family With Sequence Similarity 59, Member B; GAREML; GRB2 Associated, Regulator Of MAPK1-Like; GRB2-Associated And Regulator Of MAPK Protein-Like; GRB2-Associated And Regulator Of MAPK1-Like; KIAA2038; Protein FAM59B GAREM2 FAM59B, GAREML GRB2 associated regulator of MAPK1 subtype 2 GRB2-associated and regulator of MAPK protein 2|GRB2 associated regulator of MAPK1 2|GRB2 associated, regulator of MAPK1-like|GRB2-associated and regulator of MAPK protein-like|GRB2-associated and regulator of MAPK1-like|family with sequence similarity 59, member B|protein FAM59B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GAREM2, check out the GAREM2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GAREM2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FAM59B GAREM2 Antibody (A17028)
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No publications found for A17028
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