Product Info Summary
SKU: | A02798 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-FRS2 Antibody
SKU/Catalog Number
A02798
Size
100ul
Form
Liquid
Description
Boster Bio Anti-FRS2 Antibody catalog # A02798. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-FRS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02798)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human FRS2 around the non-phosphorylation site of Y196.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02798 is reactive to FRS2 in Human, Mouse
Applications
A02798 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.029kDa
Background of FRS2
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARFof CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARFof CDKN2A By similarity. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Hiroyasu Inada, J. Cell Biol., Oct 2001; 155: 415.
Kenneth M. Izumi, Mol. Cell. Biol., Aug 1999; 19: 5759 - 5767.
Susumu Rokudai, Mol. Cell. Biol., Dec 2002; 22: 8695 - 8708.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:40000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-FRS2 Antibody A02798
Western Blot (WB) analysis of specific cells using FRS2 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Click image to see more details
Figure 2. Western blotting validation for Anti-FRS2 Antibody A02798
Western Blot (WB) analysis of KB lysis using FRS2 antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Click image to see more details
Figure 3. Western blotting validation for Anti-FRS2 Antibody A02798
Western Blot (WB) analysis of HepG2 cells using FRS2 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For FRS2 (Source: Uniprot.org, NCBI)
Gene Name
FRS2
Full Name
Fibroblast growth factor receptor substrate 2
Weight
57.029kDa
Alternative Names
FGFR signalling adaptor; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS2; FRS2A; FRS2alpha; SNT; SNT1; SNT-1FGFR substrate 2; Suc1-associated neurotrophic factor target 1 FRS2 FRS1AA, FRS2alpha, SNT, SNT-1, SNT1, FRS2 fibroblast growth factor receptor substrate 2 fibroblast growth factor receptor substrate 2|FGFR signalling adaptor|FGFR substrate 2|FGFR-signaling adaptor SNT|epididymis secretory sperm binding protein|suc1-associated neurotrophic factor target 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FRS2, check out the FRS2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FRS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FRS2 Antibody (A02798)
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No publications found for A02798
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