|Reactivity||Human, Mouse, Rat|
|Ig Isotype||Mouse IgG2a|
|Product Name||Anti-GAP43 Antibody (Monoclonal, GAP-7B10)|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Mouse IgG monoclonal antibody for GAP43, growth associated protein 43 (GAP43) detection. Tested with WB, IHC-P, IHC-F in Human; mouse; rat. No cross reactivity with otherproteins.|
|Cite This Product||Anti-GAP43 Antibody (Monoclonal, GAP-7B10) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1042)|
|Immunogen||GAP-43 from neonatal rat forebrain membranes.|
|Reactivity||Human, Mouse, Rat|
Assay Dilutions Overview
Immunohistochemistry(Paraffin-embedded Section), 1-2μg/ml, Human, mouse, rat, By Heat
Immunohistochemistry(Frozen Section), 1-2μg/ml, Human, mouse, rat, -
Western blot, 0.5-1μg/ml, Human, mouse, rat
Boster's Secondary Antibodies And IHC, WB Kits
The following reagents are used to generate the images below.Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).
Images And Assay Conditions
Anti- GAP43 antibody, MA1042, IHC(P)
IHC(P): Rat Cardiac Muscle Tissue
Protein Target Info (Source: Uniprot.org)
|Alternative Names||Neuromodulin;Axonal membrane protein GAP-43;Growth-associated protein 43;Protein F1;Gap43;|
|Subcellular Localization||Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane ; Peripheral membrane protein . Cytoplasmic surface of growth cone and synaptic plasma membranes.|
|Molecular Weight||23603 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). .|
|Research Areas||Axonal Guidance Proteins, Cell Type Marker, Growth And Development, Neurology Process, Neuron Marker, Neuroscience, Synapse Marker
*You can search these to find other products in these research areas.
|Background||GAP43 is expressed by developing and regenerating neurons, and to a lesser extent, reactive glial cells. It is used widely to specifically label injured neurons and to score neuronal regeneration. GAP43 is also a neuronal growth cone protein thought to be involved in pathfinding. GAP43 is considered to be a crucial component of an effective regenerative response in the nervous system.|
Other Recommended Resources
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