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- Table of Contents
Neuromodulin Antibodies
AND GAP43 ELISA kits, Neuromodulin Proteins
Many biological assays use antibodies to detect Neuromodulin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neuromodulin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neuromodulin antibodies...
Designing a Western blot for Neuromodulin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GAP43 Western Blot GuideGAP43 Infographic by Boster Bio
All GAP43 Products
Product
Figures
Specificity
Applications
Price
Anti-GAP43 Antibody Picoband®
11 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01868-1
100 μg/vial
Cat # A01868-1
100 μg/vial
Anti-Neuromodulin GAP43 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1037
100 μg/vial
Cat # PA1037
100 μg/vial
Anti-GAP43 Antibody Picoband®
2 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # A01868
100 μg/vial
Cat # A01868
100 μg/vial
Human, Mouse
ELISA, IHC, WB
$370
Cat # A01876-1
100 μg/vial
Cat # A01876-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01868
100 μl
Cat # M01868
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01868-5
20μL, 40μL, 100μL, 200μL
Cat # M01868-5
20μL, 40μL, 100μL, 200μL
GAP43 Overview
Facts about Neuromodulin.
Neuromodulin (GAP43)
This protein is related to nerve growth. It's a major component of the motile"growth cones" that form the tips of elongating axons.
Plays a role in axonal and dendritic filopodia induction. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GAP43 |
| Uniprot: | P17677 |
| Entrez: | 2596 |
Family
| Belongs to: |
|---|
| neuromodulin family |
Alternative Names
Axonal membrane protein GAP-43; B-50; Basp2; calmodulin-binding protein P-57; GAP43; GAP-43; growth associated protein 43; Growth-associated protein 43; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; PP46; protein F1
Molecular Weight
Mass (kDA):
24.803 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q13.31 |
| Sequence: | 3; NC_000003.12 (115623510..115721485) |
Subcellular Localizations
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Cytoplasm. Cytoplasmic surface of growth cone and synaptic plasma membranes.
Diseases
- Nervousness
- Neuroblastoma
- Tissue Adhesions
- Infarction
- Nerve Damage
- Inflammation
- Pain
- Neoplasms
- Alzheimer's Disease
- Nerve Degeneration
- Myocardial Infarction
- Cardiac Fibrillation
Interacting Proteins
- PRKCD
- PSEN1
Pathways
- Regeneration
- Localization
- Innervation
- Cell Adhesion
- Transport
- Neurogenesis
- Pathogenesis
- Brain Development
- Cell Death
- Cell Differentiation
- Cell Growth
- Cell Proliferation
- Cell Cycle
PTMs
- Phosphorylation
- Myristoylation
- Palmitoylation
- Cleavage
Research Areas
- Cancer
- Cellular Markers
- Growth and Development
- Neuronal Cell Markers
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GAP43
bosterbio.com/bosterbio-gene-info-cards/GAP43
References
PMID: 3272162 by Kosik K.S., et al. Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human.
PMID: 3272163 by Ng S.-C., et al. Cloning of human GAP-43: growth association and ischemic resurgence.
16 Publications of Boster Neuromodulin Antibodies & ELISA Kits
- PubMed ID: 10.1016/S1673-5374(07)60060-7, Volatile of alkyd varnish inhibits the expression of neuronal growth associated ...
- PubMed ID: 10.1016/j.brainres.2006.09.058, Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in ...
- PubMed ID: 10.1007/s12035-015-9394-9, Regulation of Intracellular Structural Tension by Talin in the Axon Growth and R...
- PubMed ID: 10.1007/s10571-016-0374-z, Minocycline Promotes Neurite Outgrowth of PC12 Cells Exposed to Oxygen-Glucose D...
- PubMed ID: , Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrop...
- PubMed ID: , ALK is a therapeutic target for lethal sepsis
- PubMed ID: -, Ou Qiao,Xinyu Zhang,Yi Zhang et al.Cerebralcare Granule® enhances memantine hyd...
- PubMed ID: 26136892, Fructus Corni extract-induced neuritogenesis in PC12 cells is associated with th...
- PubMed ID: 26238991, Lentiviral-mediated growth-associated protein-43 modification of bone marrow mes...
- PubMed ID: 29707580, Liu Z, Liu H, Zeng ZH. Biomed Res Int. 2018 Mar 7;2018:8697913. doi: 10.1155/201...
- PubMed ID: 28054637, Liu H, Lv P, Zhu Y, Wu H, Zhang K, Xu F, Zheng L, Zhao J. Sci Rep. 2017 Jan 5;7:...
- PubMed ID: 28394221, Yuan Q, Sun L, Yu H, An C, Biosci Biotechnol Biochem. 2017 Apr 10:1-8. doi: 10.1...
- PubMed ID: 25352418, Zou H, Ding Y, Shi W, Xu X, Gong A, Zhang Z, Liu J. Cell Mol Neurobiol. 2015 Apr...
- PubMed ID: 25665754, Zou H, Ding Y, Wang K, Xiong E, Peng W, Du F, Zhang Z, Liu J, Gong A. Neuroscien...
- PubMed ID: 23740553, Nie X, Deng M, Yang M, Liu L, Zhang Y, Wen X. Cell Biochem Biophys. 2014 Jan;68(...
- PubMed ID: 24457043, Chen Y, Wei G, Nie H, Lin Y, Tian H, Liu Y, Yu X, Cheng S, Yan R, Wang Q, Liu Dh...
*More publications can be found for each product on its corresponding product page