Anti-GluR4 GRM4 Antibody

Product Name

Anti-GluR4 GRM4 Antibody

View all mGluR4 Antibodies

SKU/Catalog Number

A06552

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-GluR4 GRM4 Antibody (Catalog # A06552). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GluR4 GRM4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06552)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human GluR4.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A06552 is reactive to GRM4 in Human, Mouse, Rat

Applications

A06552 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

101.868kDa

Background of mGluR4

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Susana Santos Correia, J. Biol. Chem., Feb 2003; 278: 6307 - 6313.
Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224.
Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224.
Peyman Golshani, PNAS, Mar 2001; 98: 4172.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

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Western blot analysis of extracts from JK cells (Lane 2), using mGluR4 antiobdy A06552. The lane on the left is treated with synthesized peptide.

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Western blot analysis of extracts from 293 cells, untreated or treated with Forskolin (40nM, 30mins), using GluR4 antibody A06552.

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Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR4 antibody A06552.

Gene/Protein Information For GRM4 (Source: Uniprot.org, NCBI)

Alternative Names

glutamate receptor, metabotropic 4; GPRC1D; GPRC1Dmetabotropic glutamate receptor 4; GRM4; MGC177594; mGlu4; mGluR4; MGLUR4glutamate metabotropic receptor 4 GRM4 GPRC1D, MGLUR4, mGlu4 glutamate metabotropic receptor 4 metabotropic glutamate receptor 4|glutamate receptor, metabotropic 4

For more info on GRM4, check out the GRM4 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GRM4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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