Anti-Histone deacetylase 10 HDAC10 Antibody

Product Name

Anti-Histone deacetylase 10 HDAC10 Antibody

View all HDAC10 Antibodies

SKU/Catalog Number

A05215-1

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Histone deacetylase 10 HDAC10 Antibody (Catalog # A05215-1). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Histone deacetylase 10 HDAC10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05215-1)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human HDAC10.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05215-1 is reactive to HDAC10 in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

111 kDa

Calculated molecular weight

71445 MW

Background of HDAC10

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Jenny J. Tong, Nucleic Acids Res., Mar 2002; 30: 1114 - 1123.
Hung-Ying Kao, J. Biol. Chem., Jan 2002; 277: 187 - 193.
Denise D. Fischer, J. Biol. Chem., Feb 2002; 277: 6656 - 6666.
Matthew H. Brush, J. Biol. Chem., Feb 2004; 279: 7685 - 7691.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A05215-1 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Positive Control

Validation Images & Assay Conditions

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Western blot analysis of extracts from COS7 cells, using HDAC10 antibody A05215-1.

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Western blot analysis of extracts from JK cells (Lane 2) and cos-7 cells (Lane 3), using HDAC10 antiobdy A05215-1. The lane on the left is treated with synthesized peptide.

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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using HDAC10 antibody A05215-1.

Gene/Protein Information For HDAC10 (Source: Uniprot.org, NCBI)

Alternative Names

DKFZP761B039; EC 3.5.1.98; HD10; histone deacetylase 10; MGC149722 HDAC10 HD10 histone deacetylase 10 polyamine deacetylase HDAC10

For more info on HDAC10, check out the HDAC10 Infographic

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In this infographic, you will see the following information for HDAC10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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