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- Table of Contents
ARNT Antibodies
AND ARNT ELISA kits, ARNT Proteins
Many biological assays use antibodies to detect ARNT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARNT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARNT antibodies...
Designing a Western blot for ARNT? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ARNT Western Blot GuideDesigning an IHC experiment for ARNT? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ARNT IHC GuideARNT Infographic by Boster Bio
All ARNT Products
Product
Figures
Specificity
Applications
Price
Anti-HIF-1 alpha/HIF1A Antibody Picoband®
26 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00013-3
100 μg/vial
Cat # A00013-3
100 μg/vial
Anti-NAK/TBK1 Antibody Picoband®
8 Citations
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00261-1
100 μg/vial
Cat # A00261-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A00260-3
100 μg/vial
Cat # A00260-3
100 μg/vial
Anti-TLR4 Antibody Picoband®
2 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A00017-2
100 μg/vial
Cat # A00017-2
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00015-5
100 µg/vial
Cat # A00015-5
100 µg/vial
Anti-ATR Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A00262-3
100 μg/vial
Cat # A00262-3
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A05332-1
100 μg/vial
Cat # A05332-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # A00260-1
100 μg/vial
Cat # A00260-1
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1699
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1699
1 kit, containing one 96-well plate and all necessary reagents
ARNT Overview
Facts about Aryl hydrocarbon receptor nuclear translocator.
Aryl hydrocarbon receptor nuclear translocator (ARNT)
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding.
The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | ARNT |
| Uniprot: | P27540 |
| Entrez: | 405 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ARNT protein; ARNT; aryl hydrocarbon receptor nuclear translocator; BHLHE2; HIF1 beta; HIF-1 beta; HIF1B; HIF1BETA; HIF-1-beta; HIF1-beta; hypoxia-inducible factor 1, beta subunit; Hypoxia-inducible factor 1-beta; nuclear translocator; TANGO
Molecular Weight
Mass (kDA):
86.636 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q21.3 |
| Sequence: | 1; NC_000001.11 (150809713..150876737, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Hypoxia
- Malignant Neoplasms
- Neoplasms
- Liver Carcinoma
- Tumor Angiogenesis
- Anoxia
- Malignant Neoplasm Of Breast
- Carcinoma
- Pathologic Neovascularization
- Mammary Neoplasms
- Liver Neoplasms, Experimental
- Von Hippel-lindau Syndrome
Interacting Proteins
- AHR
- EPAS1
- HIF1A
- NCOA7
- NCOR2
Pathways
- Angiogenesis
- Localization
- Response To Hypoxia
- Cell Growth
- Cell Proliferation
- Translation
- Secretion
- Oxygen Homeostasis
- Cell Cycle
- Pathogenesis
- Glycolysis
- Transport
- Cell Death
PTMs
- Phosphorylation
- Hydroxylation
- Ubiquitination
- Methylation
- Oxidation
- Cleavage
- Dephosphorylation
Research Areas
- Angiogenesis
- Autophagy
- Cancer
- Cellular Markers
- Chromatin Research
- HIF Target Genes
- Hypoxia
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARNT
bosterbio.com/bosterbio-gene-info-cards/ARNT
References
PMID: 1852076 by Hoffman E.C., et al. Cloning of a factor required for activity of the Ah (dioxin) receptor.
PMID: 7539918 by Wang G.L., et al. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
64 Publications of Boster ARNT Antibodies & ELISA Kits
- PubMed ID: 10.3980/j.issn.2222-3959.2011.01.09, Effect of erythropoietin on the expression of HIF-1 and iNOS in retina in chroni...
- PubMed ID: 10.3892/mmr.2014.2859, HIF‑1 signaling pathway involving iNOS, COX‑2 and caspase‑9 mediates the n...
- PubMed ID: 10.3892/etm.2011.389, Improved radiosensitizing effect of the combination of etanidazole and paclitaxe...
- PubMed ID: 10.3748/wjg.v21.i7.2191, Semaphorin 4D and hypoxia-inducible factor-1α overexpression is related to prog...
- PubMed ID: 10.3727/096368911X566181, Bone Marrow Mesenchymal Stem Cells in a Three-Dimensional Gelatin Sponge Scaffol...
- PubMed ID: 10.3389/fphar.2021.648107, Curcumin Derivative Cur20 Attenuated Cerebral Ischemic Injury by Antioxidant Eff...
- PubMed ID: 10.3233/CBM-150474, Expression of BNIP3 and its correlations to hypoxia-induced autophagy and clinic...
- PubMed ID: 10.3233/BME-2011-0674, Analysis of neovascularization after implanting porous silk fibroin films in rat...
- PubMed ID: 10.1902/jop.2010.100610, The Role of Psychologic Stress‐Induced Hypoxia‐Inducible Factor‐1α in Rat...
- PubMed ID: 10.1590/1414-431X20142910, Putative role of ischemic postconditioning in a rat model of limb ischemia and r...
- PubMed ID: 10.12659/MSM.900354, Expression and Correlation of Hypoxia-Inducible Factor-1α (HIF-1α) with Pulmon...
- PubMed ID: 10.1186/s13287-020-02112-9, Intraperitoneal injection of Desferal® alleviated the age-related bone loss and...
- PubMed ID: 10.1186/s13046-016-0399-7, Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signal...
- PubMed ID: 10.1177/1534735416659358, Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precan...
- PubMed ID: 10.1111/ocr.12212, Effects of loading on chondrocyte hypoxia, HIF‐1α and VEGF in the mandibular ...
- PubMed ID: 10.1111/j.1442-2050.2010.01168.x, Various doses of fractioned irradiation modulates multidrug resistance 1 express...
- PubMed ID: 10.1111/j.1349-7006.2008.00905.x, Antisense hypoxia‐inducible factor 1α gene therapy enhances the therapeutic e...
- PubMed ID: 10.1111/febs.12577, Up‐regulation of survivin by AKT and hypoxia‐inducible factor 1α contribut...
- PubMed ID: 10.1097/CJI.0b013e318213cd12, Combinational Therapy of Interferon-α and Chemotherapy Normalizes Tumor Vascula...
- PubMed ID: 10.1089/hum.2008.164, Antisense Hypoxia-Inducible Factor-1α Augments Transcatheter Arterial Embolizat...
- PubMed ID: 10.1038/s41419-020-02781-7, p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox ...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page