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- Table of Contents
1 Citations 6 Q&As
Facts about Aryl hydrocarbon receptor nuclear translocator.
The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity).
| Human | |
|---|---|
| Gene Name: | ARNT |
| Uniprot: | P27540 |
| Entrez: | 405 |

| Belongs to: |
|---|
| No superfamily |

ARNT protein; ARNT; aryl hydrocarbon receptor nuclear translocator; BHLHE2; HIF1 beta; HIF-1 beta; HIF1B; HIF1BETA; HIF-1-beta; HIF1-beta; hypoxia-inducible factor 1, beta subunit; Hypoxia-inducible factor 1-beta; nuclear translocator; TANGO
Mass (kDA):
86.636 kDA

| Human | |
|---|---|
| Location: | 1q21.3 |
| Sequence: | 1; NC_000001.11 (150809713..150876737, complement) |
Nucleus.






PMID: 1852076 by Hoffman E.C., et al. Cloning of a factor required for activity of the Ah (dioxin) receptor.
PMID: 7539918 by Wang G.L., et al. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.