Product Info Summary
SKU: | A02652-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-IFIT1 Antibody
SKU/Catalog Number
A02652-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IFIT1 Antibody (Catalog # A02652-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
IFIT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-IFIT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02652-1)
Host
Rabbit
Contents
IFIT1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
IFIT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT1. The immunogen is located within amino acids 290 - 340 of IFIT1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IFIT1 antibody is human, mouse and rat reactive. At least three isoforms of IFIT1 are known to exist. This antibody is predicted to not cross-react with other members of the IFIT protein family.
Reactive Species
A02652-1 is reactive to IFIT1 in Human, Mouse, Rat
Applications
A02652-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
55.36kDa
Background of IFIT1
The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IFIT1 antibody can be used for detection of IFIT1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IFIT1 in rat small intestine tissue lysate with IFIT1 antibody at 1 μg/ml.
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Immunohistochemistry of IFIT1 in human small intestine tissue with IFIT1 antibody at 5 μg/mL.
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Immunofluorescence of IFIT1 in human small intestine tissue with IFIT1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For IFIT1 (Source: Uniprot.org, NCBI)
Gene Name
IFIT1
Full Name
Interferon-induced protein with tetratricopeptide repeats 1
Weight
55.36kDa
Superfamily
IFIT family
Alternative Names
G10P1C56; GARG-16; IFI56IFI-56; IFI-56K; IFIT-1; IFNAI1ISG56; Interferon, alpha-inducible protein (MW 56kD); Interferon-induced 56 kDa protein; interferon-induced protein 56; interferon-induced protein with tetratricopeptide repeats 1; p56; RNM561 IFIT1 C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561 interferon induced protein with tetratricopeptide repeats 1 interferon-induced protein with tetratricopeptide repeats 1|interferon, alpha-inducible protein (MW 56kD)|interferon-induced 56 kDa protein|interferon-inducible mRNA 561
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IFIT1, check out the IFIT1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IFIT1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IFIT1 Antibody (A02652-1)
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No publications found for A02652-1
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Customer Reviews
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