Anti-IGFBP3 Antibody

IGFBP-3 antibody

Boster Bio Anti-IGFBP3 Antibody catalog # PA1498. Tested in WB applications. This antibody reacts with Human, Rat. Cited in 3 publication(s).

Product Info Summary

SKU: PA1498
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-IGFBP3 Antibody

View all IGFBP-3 Antibodies

SKU/Catalog Number

PA1498

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-IGFBP3 Antibody catalog # PA1498. Tested in WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IGFBP3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1498)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human IGFBP-3 (182-198aa IKKGHAKDSQRYKVDYE).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1498 is reactive to IGFBP3 in Human, Rat

Applications

PA1498 is guaranteed for WB Boster Guarantee

Background of IGFBP-3

IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat

Validation Images & Assay Conditions

Gene/Protein Information For IGFBP3 (Source: Uniprot.org, NCBI)

Uniprot ID

P17936

Gene ID

3486

Gene Name

IGFBP3

Full Name

Insulin-like growth factor-binding protein 3

Weight

31.674kDa

Alternative Names

acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; growth hormone-dependent binding protein; IBP-3; IBP3BP-53; IGF-binding protein 3; IGFBP3; IGFBP-3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3 IGFBP3 BP-53, IBP3 insulin like growth factor binding protein 3 insulin-like growth factor-binding protein 3|IBP-3|IGF-binding protein 3|IGFBP-3|acid stable subunit of the 140 K IGF complex|binding protein 29|binding protein 53|growth hormone-dependent binding protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on IGFBP3, check out the IGFBP3 Infographic

IGFBP3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IGFBP3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

PA1498 has been cited in 3 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Correlation between insulin%u2011like growth factor binding protein 3 and metastasis%u2011associated gene 1 protein in esophageal squamous cell carcinoma

Pu Xy, Zheng Xg, Zhang Y, Xiao Hj, Xu Zp, Liu Jm, Wang Hp, Wen Am, Zhou Xx, Wu Yl. J Sex Med. 2011 Aug;8(8):2181-90. Doi: 10.1111/J.1743-6109.2011.02318.X. Epub 2011 May 19. Higher Expression Of Mrna And Protein Of Insulin-Like Growth Factor Bindi...

Pu Xy, Wen Am, Liu Jm, Zheng Xg, Xiao Hj, Xu Zp, Wang Hp, Li D, Zhang Rl. J Urol. 2014 Sep;192(3):990-6. Doi: 10.1016/J.Juro.2014.02.042. Epub 2014 Feb 24. Shrna Constructs Targeting Igfbp-3 Alleviate Age Related Erectile Dysfunction In The Rat.

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1 Customer Q&As for Anti-IGFBP3 Antibody

Question

Can PA1498 detect mouse IGFBP3?

Verified customer

Asked: 2019-04-25

Answer

The WB and IHC test result on mouse samples are not good. We do not recommend using the Anti-IGFBP3 Antibody (PA1498) on mouse samples.

Boster Scientific Support

Answered: 2019-05-08

Size

Conjugation

Total: $315

SKU:PA1498

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PA1498
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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