Product Info Summary
SKU: | A04101 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-IGFBP6 Antibody
SKU/Catalog Number
A04101
Size
100ul
Form
Liquid
Description
Boster Bio Anti-IGFBP6 Antibody catalog # A04101. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IGFBP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04101)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human IGFBP6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04101 is reactive to IGFBP6 in Human
Applications
A04101 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
25.322kDa
Background of IGFBP-6
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons By similarity.
Mitsutoshi Nakada, Cancer Res., Sep 2006; 66: 8492 - 8500.
Klas Kullander, Genes & Dev., Apr 2001; 15: 877.
M. Douglas Benson, PNAS, Jul 2005; 102: 10694 - 10699.
Stephanie R. Kadison, J. Neurosci., Aug 2006; 26: 8909 - 8914.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:20000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-IGFBP6 Antibody A04101
Western Blot (WB) analysis of K562 cells using IGFBP6 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For IGFBP6 (Source: Uniprot.org, NCBI)
Gene Name
IGFBP6
Full Name
Insulin-like growth factor-binding protein 6
Weight
25.322kDa
Alternative Names
IBP6; IBP-6; IGF binding protein 6; IGF-binding protein 6; IGFBP6; IGFBP-6; insulin-like growth factor binding protein 6; insulin-like growth factor-binding protein 6 IGFBP6 IBP6 insulin like growth factor binding protein 6 insulin-like growth factor-binding protein 6|IBP-6|IGF binding protein 6|IGFBP-6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IGFBP6, check out the IGFBP6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IGFBP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IGFBP6 Antibody (A04101)
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No publications found for A04101
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Customer Reviews
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