Anti-IL-19 Antibody

Product Name

Anti-IL-19 Antibody

View all IL-19 Antibodies

SKU/Catalog Number

A04434

Size

100μl

Form

Liquid

Description

Boster Bio Anti-IL-19 Antibody catalog # A04434. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IL-19 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04434)

Host

Rabbit

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Polyclonal

Clone Number

3F8

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 51-100.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04434 is reactive to IL19 in Human, Rat

Applications

A04434 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

20.452kDa

Background of IL-19

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript rTS alpha vary inversely when cell-growth progresses from late-log to plateau phase. Diseases associated with Thymidylate synthase include Rectal Neoplasm and Dihydropyrimidine Dehydrogenase Deficiency. Anti-Thymidylate synthase is useful for researchers interested in Circadian Rhythm, Metabolism and cell cycle research.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-2000
IHC-P, 1:50-300

Validation Images & Assay Conditions

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Western blot analysis of rat brain lysate, antibody was diluted at 500. Secondary antibody was diluted at 1:20000.

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Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200.

Gene/Protein Information For IL19 (Source: Uniprot.org, NCBI)

Alternative Names

IL-10C; IL19; IL-19; interleukin 19; MDA1; melanoma differentiation associated protein-like protein; NG.1Melanoma differentiation-associated protein-like protein; ZMDA1interleukin-19 IL19 IL-10C, MDA1, NG.1, ZMDA1 interleukin 19 interleukin-19|melanoma differentiation associated protein-like protein

For more info on IL19, check out the IL19 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IL19: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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