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Product Info Summary
| SKU: | A01385 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-ITK Antibody
SKU/Catalog Number
A01385
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ITK Antibody catalog # A01385. Tested in IHC, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ITK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01385)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ITK
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01385 is reactive to ITK in Human, Mouse
Applications
A01385 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
71.831kDa
Background of ITK
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
Abujiang Pataer, et,al. (2002) Cancer Res ; 62: 2239.
K. D. Ryman, et,al. (2005) J. Virol ; 79: 1487 - 1499.
Susana Guerra, et,al. (2006) J. Biol. Chem ; 281: 18734 - 18745.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-p 1:50-200, WB 1:500-2000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ITK (Source: Uniprot.org, NCBI)
Gene Name
ITK
Full Name
Tyrosine-protein kinase ITK/TSK
Weight
71.831kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.10; EC 2.7.10.2; EMT; EMTMGC126257; homolog of mouse T-cell itk/tsk; IL2-inducible T-cell kinase; ITK; Kinase EMT; LYK; LYKMGC126258; PSCTK2; T-cell-specific kinase; Tcsk; tyrosine-protein kinase ITK/TSK; Tyrosine-protein kinase Lyk ITK EMT, LPFS1, LYK, PSCTK2 IL2 inducible T cell kinase tyrosine-protein kinase ITK/TSK|IL-2-inducible T-cell kinase|T-cell-specific kinase|homolog of mouse T-cell itk/tsk|interleukin-2-inducible T-cell kinase|kinase EMT|tyrosine-protein kinase LYK
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ITK, check out the ITK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ITK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ITK Antibody (A01385)
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No publications found for A01385
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Customer Reviews
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