Product Info Summary
SKU: | A04297 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, WB |
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Product info
Product Name
Anti-JNK3 (K391) MAPK10 Antibody
SKU/Catalog Number
A04297
Size
100ul
Form
Liquid
Description
Boster Bio Anti-JNK3 (K391) MAPK10 Antibody catalog # A04297. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-JNK3 (K391) MAPK10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04297)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human WTAP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04297 is reactive to MAPK10 in Human, Mouse, Rat
Applications
A04297 is guaranteed for IF, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
52.585kDa
Background of JNK3
Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.
Ortega A., J. Biol. Chem. 278:3040-3047(2003).
Nagase T., DNA Res. 2:37-43(1995).
Mungall A.J., Nature 425:805-811(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For MAPK10 (Source: Uniprot.org, NCBI)
Gene Name
MAPK10
Full Name
Mitogen-activated protein kinase 10
Weight
52.585kDa
Superfamily
protein kinase superfamily
Alternative Names
c-Jun N-terminal kinase 3; EC 2.7.11; EC 2.7.11.24; JNK3 alpha protein kinase; JNK3; JNK3A; JNK3FLJ12099; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10; MGC50974; mitogen-activated protein kinase 10; p493F12; p54bSAPK; PRKM10FLJ33785; SAPK1 beta; stress activated protein kinase beta; Stress-activated protein kinase JNK3 MAPK10 JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK mitogen-activated protein kinase 10 mitogen-activated protein kinase 10|JNK3 alpha protein kinase|MAP kinase 10|MAP kinase p49 3F12|c-Jun N-terminal kinase 3|stress activated protein kinase beta|stress-activated protein kinase 1b|stress-activated protein kinase JNK3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MAPK10, check out the MAPK10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MAPK10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-JNK3 (K391) MAPK10 Antibody (A04297)
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No publications found for A04297
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Recommended Resources
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