Anti-JNK3 MAPK10 Antibody

JNK3 antibody

Boster Bio Anti-JNK3 MAPK10 Antibody catalog # A04297-1. Tested in WB,ICC/IF,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A04297-1
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IF, ICC, WB

Product Name

Anti-JNK3 MAPK10 Antibody

View all JNK3 Antibodies

SKU/Catalog Number

A04297-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-JNK3 MAPK10 Antibody catalog # A04297-1. Tested in WB,ICC/IF,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-JNK3 MAPK10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04297-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from C-terminal of human WTAP.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04297-1 is reactive to MAPK10 in Human, Mouse, Rat

Applications

A04297-1 is guaranteed for Flow Cytometry, IF, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

52.585kDa

Background of JNK3

Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.

Ortega A., J. Biol. Chem. 278:3040-3047(2003).
Nagase T., DNA Res. 2:37-43(1995).
Mungall A.J., Nature 425:805-811(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500
FC: 1:50-1:100
ICC: 1:100-1:500

Validation Images & Assay Conditions

Gene/Protein Information For MAPK10 (Source: Uniprot.org, NCBI)

Gene Name

MAPK10

Full Name

Mitogen-activated protein kinase 10

Weight

52.585kDa

Superfamily

protein kinase superfamily

Alternative Names

c-Jun N-terminal kinase 3; EC 2.7.11; EC 2.7.11.24; JNK3 alpha protein kinase; JNK3; JNK3A; JNK3FLJ12099; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10; MGC50974; mitogen-activated protein kinase 10; p493F12; p54bSAPK; PRKM10FLJ33785; SAPK1 beta; stress activated protein kinase beta; Stress-activated protein kinase JNK3 MAPK10 JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK mitogen-activated protein kinase 10 mitogen-activated protein kinase 10|JNK3 alpha protein kinase|MAP kinase 10|MAP kinase p49 3F12|c-Jun N-terminal kinase 3|stress activated protein kinase beta|stress-activated protein kinase 1b|stress-activated protein kinase JNK3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MAPK10, check out the MAPK10 Infographic

MAPK10 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAPK10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A04297-1-100ul

100ul

$405

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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