Product Info Summary
SKU: | A01106-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IP, IHC, WB |
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Product info
Product Name
Anti-Liver Arginase ARG1 Antibody
View all Arginase 1/ARG1/liver Arginase Antibodies
SKU/Catalog Number
A01106-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Liver Arginase ARG1 Antibody catalog # A01106-2. Tested in WB,IHC,IP applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Liver Arginase ARG1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01106-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Pdcd-4 around the phosphorylation site of S67.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01106-2 is reactive to ARG1 in Human
Applications
A01106-2 is guaranteed for IP, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
34.735kDa
Background of Arginase 1/ARG1/liver Arginase
Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699
Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789
Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662
Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031
Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2,000
IHC: 1:50-1:200
IP: 1:10-1:50
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of ARG1 using Anti-Liver Arginase ARG1 Antibody (A01106-2).
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Liver Arginase antibody. Counter stained with hematoxylin.For more protocol information of IHC
Click image to see more details
Figure 1. Western blotting validation for Anti-Liver Arginase ARG1 Antibody A01106-2
Western blot analysis of Liver Arginase on human liver tissue lysate using anti-Liver Arginase antibody at 1/500 dilution.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For ARG1 (Source: Uniprot.org, NCBI)
Gene Name
ARG1
Full Name
Arginase-1
Weight
34.735kDa
Superfamily
arginase family
Alternative Names
AI; ARG1; Arginase 1; arginase, liver; Arginase-1; EC 3.5.3.1; Liver Arginase; Liver-type arginase; PGIF; Type I Arginase ARG1 arginase 1 arginase-1|arginase, liver|liver-type arginase|type I arginase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ARG1, check out the ARG1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ARG1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Liver Arginase ARG1 Antibody (A01106-2)
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No publications found for A01106-2
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