Product Info Summary
SKU: | A02323 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-MASP2 Antibody
SKU/Catalog Number
A02323
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MASP2 Antibody catalog # A02323. Tested in WB applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MASP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02323)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human HEXIM1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02323 is reactive to MASP2 in Human, Mouse
Applications
A02323 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
75.702kDa
Background of MASP2
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Kusuhara M., Biomed. Res. 20:273-279(1999).
Wittmann B.M., Cancer Res. 63:5151-5158(2003).
Ouchida R., Genes Cells 8:95-107(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-MASP2 Antibody A02323
Western blot (WB) analysis of MASP2 polyclonal antibody at 1:500 dilutionLane1:Hela cell lysate
Lane2:sp2/0 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For MASP2 (Source: Uniprot.org, NCBI)
Gene Name
MASP2
Full Name
Mannan-binding lectin serine protease 2
Weight
75.702kDa
Superfamily
peptidase S1 family
Alternative Names
EC 3.4.21; EC 3.4.21.104; mannan-binding lectin serine peptidase 1 pseudogene 1; mannan-binding lectin serine peptidase 2; mannan-binding lectin serine protease 1 pseudogene 1; mannan-binding lectin serine protease 2; Mannose-binding protein-associated serine protease 2; MAP19; MASP1P1; MASP-2; MBL-associated plasma protein of 19 kD; MBL-associated serine protease 2; small MBL-associated protein; sMAP MASP2 MAP19, MASP-2, MASP1P1, sMAP MBL associated serine protease 2 mannan-binding lectin serine protease 2|MBL-associated plasma protein of 19 kD|mannan binding lectin serine peptidase 2|mannan-binding lectin serine peptidase 1 pseudogene 1|mannan-binding lectin serine protease 1 pseudogene 1|mannose-binding lectin associated protein 19|mannose-binding lectin-associated serine protease 2|mannose-binding protein-associated serine protease 2|small MBL-associated protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MASP2, check out the MASP2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MASP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MASP2 Antibody (A02323)
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No publications found for A02323
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