Product Info Summary
SKU: | A03486Y108 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-MKP-2 (Y108) DUSP4 Antibody
SKU/Catalog Number
A03486Y108
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MKP-2 (Y108) DUSP4 Antibody catalog # A03486Y108. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MKP-2 (Y108) DUSP4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03486Y108)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Casein Kinase IIbeta around the phosphorylation site of S209.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03486Y108 is reactive to DUSP4 in Human, Mouse, Rat
Applications
A03486Y108 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
42.953kDa
Background of DUSP4
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho.
Wirth J.A., J. Cell Sci. 109:653-661(1996).
Grewal P.K., Gene 240:389-398(1999).
Post P.L., J. Cell Sci. 111:941-950(1998).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of DUSP4 using Anti-MKP-2 (Y108) DUSP4 Antibody (A03486Y108).
Immunohistochemistry (IHC) analyzes of MKP-2 (Y108) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.For more protocol information of IHC
Protein Target Info & Infographic
Gene/Protein Information For DUSP4 (Source: Uniprot.org, NCBI)
Gene Name
DUSP4
Full Name
Dual specificity protein phosphatase 4
Weight
42.953kDa
Superfamily
protein-tyrosine phosphatase family
Alternative Names
dual specificity phosphatase 4; Dual specificity protein phosphatase hVH2; EC 3.1.3.16; EC 3.1.3.48; HVH2serine/threonine specific protein phosphatase; MAP kinase phosphatase 2; Mitogen-activated protein kinase phosphatase 2; MKP-2dual specificity protein phosphatase 4; MKP2VH1 homologous phosphatase 2; TYP; VH2 DUSP4 HVH2, MKP-2, MKP2, TYP dual specificity phosphatase 4 dual specificity protein phosphatase 4|MAP kinase phosphatase 2|VH1 homologous phosphatase 2|dual specificity protein phosphatase hVH2|mitogen-activated protein kinase phosphatase 2|serine/threonine specific protein phosphatase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DUSP4, check out the DUSP4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DUSP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MKP-2 (Y108) DUSP4 Antibody (A03486Y108)
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No publications found for A03486Y108
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Customer Reviews
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Customer Q&As
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