Anti-NFkB-p100 (Ab-866) NFKB2 Antibody

NFKB2 antibody

Boster Bio Anti-NFkB-p100 (Ab-866) NFKB2 Antibody (Catalog # A01228-1). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat. Cited in 10 publication(s).

Product Info Summary

SKU: A01228-1
Size: 100 µl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, WB

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Product Name

Anti-NFkB-p100 (Ab-866) NFKB2 Antibody

View all NFKB2 Antibodies

SKU/Catalog Number

A01228-1

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-NFkB-p100 (Ab-866) NFKB2 Antibody (Catalog # A01228-1). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NFkB-p100 (Ab-866) NFKB2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01228-1)

Host

Rabbit

Contents

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Clone Number

2D3

Isotype

IgG

Immunogen

Peptide sequence around aa.864~868 (E-D-S-A-Y) derived from Human NFkB-p100.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01228-1 is reactive to NFKB2 in Human, Mouse, Rat

Applications

A01228-1 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

96.749kDa

Background of NFKB2

NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.

Qu Z, et al. (2004) J Biol Chem. 279(43): 44563-44572.
Xiao G, et al. (2001) Mol Cell. 7(2): 401-409.
Baeuerle P A, et al. (1994) Annu Rev Immunol. 12:141-179.
Baeuerle P A, et al. (1996) Cell 87:13-20.
Haskill S, et al. (1991) Cell 65:1281-1289.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Predicted MW: 120 kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Validation Images & Assay Conditions

Gene/Protein Information For NFKB2 (Source: Uniprot.org, NCBI)

Gene Name

NFKB2

Full Name

Nuclear factor NF-kappa-B p100 subunit

Weight

96.749kDa

Alternative Names

LYT10; NFkB2; NF-kB2 NFKB2 CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52 nuclear factor kappa B subunit 2 nuclear factor NF-kappa-B p100 subunit|DNA-binding factor KBF2|NFKB, p52/p100 subunit|lymphocyte translocation chromosome 10 protein|nuclear factor Kappa-B, subunit 2|nuclear factor NF-kappa-B p52 subunit|nuclear factor of Kappa light chain gene enhancer in B cells 2|nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)|oncogene Lyt-10|transcription factor NFKB2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on NFKB2, check out the NFKB2 Infographic

NFKB2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for NFKB2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A01228-1 has been cited in 10 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model

Naringin attenuates diabetic retinopathy by inhibiting inflammation, oxidative stress and NF-%u03BAB activation in vivo and in vitro

Therapeutic effect of artemisinin on lupus nephritis mice and its mechanisms

Ursolic acid protects against ulcerative colitis via anti-inflammatory and antioxidant effects in mice

Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by inhibiting the inflammatory response

Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects

Simvastatin ameliorates renal lipidosis through the suppression of renal CXCL16 expression in mice with adriamycin-induced nephropathy.

Down-regulation of HMGB1 expression by shRNA constructs inhibits the bioactivity of urothelial carcinoma cell lines via the NF-?B pathway

Ozone preconditioning and exposure to ketamine attenuates hepatic inflammation in septic rats

Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages

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Order DetailsPrice
A01228-1

100ul

$360

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