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Product Info Summary
|Application:||IHC, ICC, WB|
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Anti-p16INK4a/CDKN2 Antibody (Monoclonal, DCS-50)
Boster Bio Anti-p16INK4a/CDKN2 Antibody (Monoclonal, DCS-50) catalog # MA1074. Tested in IHC, ICC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-p16INK4a/CDKN2 Antibody (Monoclonal, DCS-50) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1074)
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Recombinant human p16 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins
MA1074 is reactive to CDKN2A in Human
MA1074 is guaranteed for IHC, ICC, WB Boster Guarantee
Background of Cdkn2a
p16 (INK4A), also known as cyclin-dependent kinase inhibitor 2A (CDKN2A), or multiple tumor suppressor 1 (MTS1). The p16 gene (CDKN2A) was mapped to 9p21. The p16 gene encodes a negative regulator of the cell cycle. CDKN2 plays an important role during tumorigenesis or tumor progression in a significant proportion of pancreatic adenocarcinomas. Germ-line mutations in the CDKN2A tumor-suppressor gene have been linked to the development of melanoma in some families with inherited melanoma.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Immunocytochemistry , 1μg/ml, Human, -
Immunohistochemistry (Frozen Section), 1-2μg/ml, Human, -
Western blot, 0.5-1μg/ml, Human
Validation Images & Assay Conditions
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Boster Kit Box
Gene/Protein Information For CDKN2A (Source: Uniprot.Org, NCBI)
Cyclin-dependent kinase inhibitor 2A
CDKN2 cyclin-dependent kinase inhibitor family
alternative reading frame; ARF; ARF-INK4a; CDK4I; CDKN2A; Cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; INK4; INK4a; Ink4a/Arf; INK4a-ARF; mitochondrial smARF'; MTS1; p14; p14ARF; P16; p16(INK4a); p16-INK4; P16INK4A; p16-INK4a; P19; p19<ARF>; p19ARF; Pctr1 Cdkn2a|Arf, INK4A, MTS1, p16, p16Cdkn2a, p19ARF|cyclin-dependent kinase inhibitor 2A|cyclin-dependent kinase inhibitor 2A|CDK4I|Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4)|alternative reading frame|cell cycle inhibitor|cell cycle regulator|cyclin-dependent kinase 4 inhibitor A|cyclin-dependent kinase inhibitor 2a p16Ink4a|cyclin-dependent kinase inhibitor 2a p19Arf|p16-INK4|p16-INK4a*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
For more info on CDKN2A, check out the CDKN2A Infographic
We have 30,000+ of these available, one for each gene! check them out.
In this infographic you will see the following information for CDKN2A: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]
MA1074 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Construction of pETNF-P16 plasmid and its expression properties in EC9706 cell line induced by X-ray irradiation
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