Anti-PACS1 Antibody

Product Name

Anti-PACS1 Antibody

View all PACS1 Antibodies

SKU/Catalog Number

A06811-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-PACS1 Antibody (Catalog # A06811-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-PACS1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06811-1)

Host

Rabbit

Contents

PACS1 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. The immunogen is located within amino acids 430 - 480 of PACS1.

Cross-reactivity

PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.

Reactive Species

A06811-1 is reactive to PACS1 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

104.9 kDa

Background of PACS1

The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06811-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 2 μg/mL For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information PACS1

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