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Product Info Summary
| SKU: | A00282S439-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Phospho-SREBP-1 (S439) SREBF1 Antibody
SKU/Catalog Number
A00282S439-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-SREBP-1 (S439) SREBF1 Antibody catalog # A00282S439-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-SREBP-1 (S439) SREBF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00282S439-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human SREBP-1 around the phosphorylation site of S439.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00282S439-1 is reactive to SREBF1 in Human, Rat
Applications
A00282S439-1 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
121.675kDa
Background of SREBP1
HDAC-1 antibody recognizes HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) which belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Validation Images & Assay Conditions
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Figure 1. Immunohistochemistry validation of SREBF1 using Anti-Phospho-SREBP-1 (S439) SREBF1 Antibody (A00282S439-1).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°CProtein Target Info & Infographic
Gene/Protein Information For SREBF1 (Source: Uniprot.org, NCBI)
Gene Name
SREBF1
Full Name
Sterol regulatory element-binding protein 1
Weight
121.675kDa
Superfamily
SREBP family
Alternative Names
BHLHD1; Class D basic helix-loop-helix protein 1; SREBP 1c; SREBP-1; SREBP1bHLHd1SREBP-1c; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1 SREBF1 HMD, IFAP2, SREBP1, bHLHd1 sterol regulatory element binding transcription factor 1 sterol regulatory element-binding protein 1|class D basic helix-loop-helix protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SREBF1, check out the SREBF1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SREBF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-SREBP-1 (S439) SREBF1 Antibody (A00282S439-1)
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