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Product Info Summary
| SKU: | A14890 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Protein yippee-like 3 YPEL3 Antibody
SKU/Catalog Number
A14890
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Protein yippee-like 3 YPEL3 Antibody (Catalog # A14890). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
YPEL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Protein yippee-like 3 YPEL3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14890)
Host
Rabbit
Contents
YPEL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
YPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3. The immunogen is located within amino acids 20 - 70 of YPEL3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Two isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b.
Reactive Species
A14890 is reactive to Ypel3 in Human, Mouse, Rat
Applications
A14890 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
13.608kDa
Background of Ypel3
YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
YPEL3 antibody can be used for detection of YPEL3 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of YPEL3 in A-20 cell lysate with YPEL3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide
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Immunocytochemistry of YPEL3 in A20 cells with YPEL3 antibody at 2.5 μg/mL.
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Immunofluorescence of YPEL3 in A20 cells with YPEL3 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Ypel3 (Source: Uniprot.org, NCBI)
Gene Name
Ypel3
Full Name
Protein yippee-like 3
Weight
13.608kDa
Superfamily
yippee family
Alternative Names
FKSG5; MGC10500; protein yippee-like 3; yippee-like 3 (Drosophila) Ypel3|0610043B10Rik, 1190001G19Rik, S, Suap|yippee like 3|protein yippee-like 3|small ubiquitinated apoptotic protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Ypel3, check out the Ypel3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Ypel3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Protein yippee-like 3 YPEL3 Antibody (A14890)
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No publications found for A14890
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