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- Table of Contents
RIPK1 antibody (A00141-1) performs well in ELISA, IF, IHC-P, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 2 Publications
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Immunofluorescence of RIPK1 in Mouse Kidney cells with RIPK1 antibody at 20 μg/mL.
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Anti-RIPK1 Antibody
RIPK1 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, IF, IHC-P, WB |
Recommend Dilution
Application
Dilution
Species
RIPK1 antibody can be used for detection of RIPK1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-RIPK1 Antibody
View all RIPK1 Antibodies
View all RIPK1 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
RIPK1 antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
RIPK1 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1. The immunogen is located within amino acids 180 - 230 of RIPK1.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
75.9 kDa
Background of RIPK1
RIPK1 (Receptor Interacting Protein) is a crucial 74 kD adaptor kinase in several of stress-induced signaling pathways and on the crossroad of a cell's decision to live or die. RIPK1 contains an N-terminal region with homology to protein kinases, an intermediate domain capable of association with MAPKKK and a C-terminal region containing a death domain motif present in the Fas and TNFR1 intracellular domains. Full length RIPK1 is important for signallling to NFκ-B, MAPKs and necrosis, whereas caspase-8 generates a C-terminal RIPK1 cleavage fragment, promoting TNF-induced apoptosis. It is required for TNFRSF1A-mediated and TLR3-induced NF-κB activation. RIPK1-deficient mice fail to thrive, displaying extensive apoptosis in both lymphoid and adipose tissues and dying at 1-3 days of age.
Cite This Product
Anti-RIPK1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00141-1)
Publications
Application:
Species:
Chen H,Tang LJ,Tu H,Zhou YJ,Li NS,Luo XJ,Peng J.Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis.Eur J Pharmacol.2020 May 15;875:173053.doi:10.1016/j.ejphar.2020.173053.Epub 2020 Mar 2.PMID:32135123.
Species: Rat
PMID: 32135123
Tu H,Zhou YJ,Tang LJ,Xiong XM,Zhang XJ,Ali Sheikh MS,Zhang JJ,Luo XJ,Yuan C,Peng J. Combination of ponatinib with deferoxamine synergistically mitigates ischemic heart injury via simultaneous prevention of necroptosis and ferroptosis. Eur J Pharmacol.2021 Mar 3;898:173999.doi:10.1016/j.ejphar.2021.173999.Epub ahead of print.PMID:33675785.
Species: Rat
PMID: 33675785
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Product Promise
We promise Anti-RIPK1 Antibody performs excellently in relevant applications for ELISA, IF, IHC-P, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
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A00141-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 3, 2026