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Product Info Summary
| SKU: | A09733 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Slc22A17 Antibody
SKU/Catalog Number
A09733
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Slc22A17 Antibody (Catalog # A09733). Tested in ELISA, WB, IF, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Slc22A17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Slc22A17 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09733)
Host
Rabbit
Contents
Slc22A17 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Slc22A17 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Slc22A17. The immunogen is located within the last 50 amino acids of Slc22A17.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ATG4C antibody is human, mouse and rat reactive. ATG4C is predicted to not cross-react with other ATG4 proteins.
Reactive Species
A09733 is reactive to SLC22A17 in Human, Mouse, Rat
Applications
A09733 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
57.686kDa
Background of SLC22A17
The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Slc22A17 antibody can be used for detection of Slc22A17 by Western blot at 0.5 μg/mL. Antibody can also be used for immunoflourescence starting at 20 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Slc22A17 in SK-N-SH lysate with Slc22A17 antibody at 0.5 μg/mL in (A) the presence and (B) the absence of blocking peptide.
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Immunofluorescence of Slc22A17 in rat kidney tissue tissue with Slc22A17 antibody at 20 μg/mL.
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Immunofluorescence of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 20 μg/ml.
Green: Slc22A17 Antibody (A09733)
Blue: DAPI staining
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Immunohistochemistry of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 2.5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For SLC22A17 (Source: Uniprot.org, NCBI)
Gene Name
SLC22A17
Full Name
Solute carrier family 22 member 17
Weight
57.686kDa
Superfamily
major facilitator (TC 2.A.1) superfamily
Alternative Names
24p3R; BOCTNGALR3; BOIThBOIT; Brain-type organic cation transporter; Lipocalin-2 receptor; Neutrophil gelatinase-associated lipocalin receptor; NgalR; NGALR2; NGALRNGAL receptor; potent brain type organic ion transporter; solute carrier family 22 (organic cation transporter), member 17; solute carrier family 22 member 17,24p3 receptor; solute carrier family 22, member 17 SLC22A17 24p3R, BOCT, BOIT, NGALR, NGALR2, NGALR3, hBOIT solute carrier family 22 member 17 solute carrier family 22 member 17|24p3 receptor|NGAL receptor|brain-type organic cation transporter|lipocalin-2 receptor|neutrophil gelatinase-associated lipocalin receptor|potent brain type organic ion transporter|solute carrier family 22 (organic cation transporter), member 17
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC22A17, check out the SLC22A17 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC22A17: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Slc22A17 Antibody (A09733)
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No publications found for A09733
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