Click image to see more details
Product Info Summary
| SKU: | A00053-3 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-Stromal cell-derived factor 1 CXCL12 Antibody
SKU/Catalog Number
A00053-3
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Stromal cell-derived factor 1 CXCL12 Antibody (Catalog # A00053-3). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse.
Storage & Handling
CXCL12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Stromal cell-derived factor 1 CXCL12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00053-3)
Host
Rabbit
Contents
CXCL12 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12 . The immunogen is located within the last 50 amino acids of CXCL12.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CXCL12 antibody is human and mouse reactive. Multiple isoforms of CXCL12 are known to exist.
Reactive Species
A00053-3 is reactive to CXCL12 in Human, Mouse
Applications
A00053-3 is guaranteed for ELISA, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
10.666kDa
Background of CXCL12
The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CXCL12 antibody can be used for detection of CXCL12 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of CXCL12 in HeLa cell lysate with CXCL12 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Click image to see more details
Immunocytochemistry of CXCL12 in HeLa cells with CXCL12 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CXCL12 (Source: Uniprot.org, NCBI)
Gene Name
CXCL12
Full Name
Stromal cell-derived factor 1
Weight
10.666kDa
Superfamily
intercrine alpha (chemokine CxC) family
Alternative Names
chemokine (C-X-C motif) ligand 12; C-X-C motif chemokine 12; CXCL12; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; PBSFSDF-1a; Pre-B cell growth-stimulating factor; SCYB12; SDF1; SDF-1; SDF1A; SDF1B; SDF1SDF-1b; stromal cell-derived factor 1; TLSF; TLSF-a; TLSF-b; TPAR1 CXCL12 IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1 C-X-C motif chemokine ligand 12 stromal cell-derived factor 1|chemokine (C-X-C motif) ligand 12|intercrine reduced in hepatomas|pre-B cell growth-stimulating factor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CXCL12, check out the CXCL12 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CXCL12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Stromal cell-derived factor 1 CXCL12 Antibody (A00053-3)
Hello CJ!
No publications found for A00053-3
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-Stromal cell-derived factor 1 CXCL12 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-Stromal cell-derived factor 1 CXCL12 Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
