Anti-TCF4/12 Antibody

Product Name

Anti-TCF4/12 Antibody

View all TCF4 Antibodies

SKU/Catalog Number

A00674

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-TCF4/12 Antibody (Catalog # A00674). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TCF4/12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00674)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human TCF4/12.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00674 is reactive to TCF4 in Human, Mouse, Rat

Applications

A00674 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

71.308kDa

Background of TCF4

Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription By similarity. Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.

Corneliussen B., J. Virol. 65:6084-6093(1991).
Breschel T.S., Hum. Mol. Genet. 6:1855-1863(1997).
Amiel J., Am. J. Hum. Genet. 80:988-993(2007).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from HUVEC cells, using TCF4/12 antibody A00674.

Gene/Protein Information For TCF4 (Source: Uniprot.org, NCBI)

Alternative Names

BHLHB19; bHLHb19E2-2; Class B basic helix-loop-helix protein 19; Immunoglobulin transcription factor 2; ITF-2; ITF2PTHS; MGC149724; SEF-2; SEF2-1; SEF2-1A; SEF2-1B; SEF2MGC149723; SL3-3 enhancer factor 2; TCF-4; transcription factor 4 TCF4 CDG2T, E2-2, FECD3, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, TCF-4, bHLHb19 transcription factor 4 transcription factor 4|SL3-3 enhancer factor 2|class B basic helix-loop-helix protein 19|immunoglobulin transcription factor 2

For more info on TCF4, check out the TCF4 Infographic

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In this infographic, you will see the following information for TCF4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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