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Product Info Summary
| SKU: | A01541 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IHC-P |
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Product info
Product Name
Anti-Toll-like receptor 8 TLR8 Antibody
SKU/Catalog Number
A01541
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Toll-like receptor 8 TLR8 Antibody (Catalog # A01541). Tested in ELISA, IHC-P applications. This antibody reacts with Human, Mouse.
Storage & Handling
TLR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Toll-like receptor 8 TLR8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01541)
Host
Rabbit
Contents
TLR8 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TLR8 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human TLR8. The immunogen is located within the first 50 amino acids of TLR8.
Cross-reactivity
At least three isoforms of TLR8 are known to exist. TLR8 antibody is predicted to not cross-react with other TLR protein family members
Reactive Species
A01541 is reactive to TLR8 in Human, Mouse
Observed Molecular Weight
68 kDa
Calculated molecular weight
119.8 kDa
Background of TLR8
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01541 is guaranteed for ELISA, IHC-P Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLR8 antibody can be used for detection of TLR8 by immunohistochemistry at 5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Immunohistochemistry in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Immunohistochemistry of TLR8 in human thymus tissue with TLR8 antibody at 5 μg/mL.
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Immunohistochemistry of TLR8 in mouse thymus tissue with TLR8 Antibody at 5 μg/mL.
Specific Publications For Anti-Toll-like receptor 8 TLR8 Antibody (A01541)
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