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Product Info Summary
| SKU: | A00381 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Tropomyosin alpha-3 chain TPM3 Antibody
View all tropomyosin-3 Antibodies
SKU/Catalog Number
A00381
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Tropomyosin alpha-3 chain TPM3 Antibody catalog # A00381. Tested in WB applications. This antibody reacts with Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Tropomyosin alpha-3 chain TPM3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00381)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Survivin around the phosphorylation site of T34.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with eNOS or nNOS.
Reactive Species
A00381 is reactive to TPM3 in Mouse
Applications
A00381 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
32.95kDa
Background of tropomyosin-3
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
David A. Jans, J. Biol. Chem., Nov 1996; 271: 30781.
Eugene Estella, Diabetes, Aug 2006; 55: 2212 - 2219.
Yong Gu, J. Biol. Chem., May 1996; 271: 10816.
Jiuru Sun, J. Biol. Chem., Nov 1996; 271: 27802.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For TPM3 (Source: Uniprot.org, NCBI)
Gene Name
TPM3
Full Name
Tropomyosin alpha-3 chain
Weight
32.95kDa
Superfamily
tropomyosin family
Alternative Names
cytoskeletal tropomyosin TM30; FLJ41118; gamma-tropomyosin; heat-stable cytoskeletal protein 30 kDa; hscp30; hTM5; MGC14582; MGC3261; MGC72094; NEM1; OK/SW-cl.5; TM3; TM30; TM30nm; TM-5; TPMsk3; TRK; tropomyosin 3; tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin-3; tropomyosin-5 TPM3 CAPM1, CFTD, HEL-189, HEL-S-82p, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5nu, TPMsk3, TRK, hscp30, TPM3 tropomyosin 3 tropomyosin alpha-3 chain|alpha-tropomyosin, slow skeletal|cytoskeletal tropomyosin TM30|epididymis luminal protein 189|epididymis secretory sperm binding protein Li 82p|heat-stable cytoskeletal protein 30 kDa|tropomyosin 3 nu|tropomyosin gamma|tropomyosin-5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TPM3, check out the TPM3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TPM3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Tropomyosin alpha-3 chain TPM3 Antibody (A00381)
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No publications found for A00381
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