Anti-USP10 Monoclonal Antibody

Product Name

Anti-USP10 Monoclonal Antibody

View all USP10 Antibodies

SKU/Catalog Number

M03786

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-USP10 Monoclonal Antibody catalog # M03786. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-USP10 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03786)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

ADCB-21

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human USP10 Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M03786 is reactive to USP10 in Human

Applications

M03786 is guaranteed for IP, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

25 kDa

Calculated molecular weight

87.134kDa

Background of USP10

Plays a major role in tight junction-specific obliteration of the intercellular space.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50

Validation Images & Assay Conditions

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Western blot analysis of USP10 expression in A375 cell lysate.

Gene/Protein Information For USP10 (Source: Uniprot.org, NCBI)

Alternative Names

Deubiquitinating enzyme 10; EC 3.4.19.12; KIAA0190MGC2621; ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific peptidase 10; ubiquitin specific protease 10; ubiquitin thioesterase 10; Ubiquitin Thiolesterase 10; Ubiquitin-specific-processing protease 10; UBPO; Uchrp; USP10 USP10 UBPO ubiquitin specific peptidase 10 ubiquitin carboxyl-terminal hydrolase 10|deubiquitinating enzyme 10|ubiquitin specific protease 10|ubiquitin thioesterase 10|ubiquitin thiolesterase 10|ubiquitin-specific-processing protease 10

For more info on USP10, check out the USP10 Infographic

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In this infographic, you will see the following information for USP10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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