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Product Info Summary
| SKU: | A05225 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | Flow Cytometry, IP, IF, ICC, WB |
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Product info
Product Name
Anti-USP11 Antibody
SKU/Catalog Number
A05225
Size
100ul
Form
Liquid
Description
Boster Bio Anti-USP11 Antibody catalog # A05225. Tested in WB,ICC/IF,IP,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-USP11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05225)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ACAD-9
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05225 is reactive to USP11 in Human, Mouse, Rat
Applications
A05225 is guaranteed for Flow Cytometry, IP, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
109.817kDa
Background of USP11
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Jenny J. Tong, Nucleic Acids Res., Mar 2002; 30: 1114 - 1123.
Hung-Ying Kao, J. Biol. Chem., Jan 2002; 277: 187 - 193.
Denise D. Fischer, J. Biol. Chem., Feb 2002; 277: 6656 - 6666.
Matthew H. Brush, J. Biol. Chem., Feb 2004; 279: 7685 - 7691.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1,000
ICC: 1:50-1:200
FC: 1:50-1:100
Validation Images & Assay Conditions
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Figure 2. Immunocytochemistry staining of USP11 using Anti-USP11 Antibody (A05225).
ICC staining USP11 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde
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Figure 1. Western blotting validation for Anti-USP11 Antibody A05225
Western blot analysis of USP11 on 293T cell using anti-USP11 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For USP11 (Source: Uniprot.org, NCBI)
Gene Name
USP11
Full Name
Ubiquitin carboxyl-terminal hydrolase 11
Weight
109.817kDa
Superfamily
peptidase C19 family
Alternative Names
Deubiquitinating enzyme 11; EC 3.1.2.15; EC 3.4.19.12; ubiquitin carboxyl-terminal hydrolase 11; ubiquitin specific peptidase 11; ubiquitin specific protease 11; Ubiquitin Thioesterase 11; Ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; Ubiquitin-specific-processing protease 11; UHX1; UHX1ubiquitin carboxyl-terminal hydrolase, X-linked; USP11 USP11 UHX1 ubiquitin specific peptidase 11 ubiquitin carboxyl-terminal hydrolase 11|deubiquitinating enzyme 11|ubiquitin carboxyl-terminal hydrolase, X-linked|ubiquitin thioesterase 11|ubiquitin thiolesterase 11|ubiquitin-specific processing protease 11
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on USP11, check out the USP11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for USP11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-USP11 Antibody (A05225)
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No publications found for A05225
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Customer Reviews
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