Anti-ZFYVE19 Antibody

Product Name

Anti-ZFYVE19 Antibody

View all Zfyve19 Antibodies

SKU/Catalog Number

A11198

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-ZFYVE19 Antibody (Catalog # A11198). Tested in WB, IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ZFYVE19 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11198)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human ZFYVE19.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A11198 is reactive to Zfyve19 in Human

Applications

A11198 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

43.272kDa

Background of Zfyve19

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

Chinwalla V., Oncogene 22:1400-1410(2003).
Ota T., Nat. Genet. 36:40-45(2004).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

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Western blot analysis of extracts from HT-29 cells, using ZFYVE19 antibody A11198.

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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ZFYVE19 antibody A11198.

Gene/Protein Information For Zfyve19 (Source: Uniprot.org, NCBI)

Alternative Names

FLJ14840; MLL partner containing FYVE domain; MPFYVE; zinc finger FYVE domain-containing protein 19; zinc finger, FYVE domain containing 19

For more info on Zfyve19, check out the Zfyve19 Infographic

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In this infographic, you will see the following information for Zfyve19: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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