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- Table of Contents
ABCC4 Antibodies
AND ABCC4 ELISA kits, ABCC4 Proteins
Many biological assays use antibodies to detect ABCC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCC4 antibodies...
Designing a Western blot for ABCC4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ABCC4 Western Blot GuideDesigning an IHC experiment for ABCC4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ABCC4 IHC GuideABCC4 Infographic by Boster Bio
All ABCC4 Products
Product
Figures
Specificity
Applications
Price
Anti-MRP4/ABCC4 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9144
100 μg/vial
Cat # PB9144
100 μg/vial
Anti-MRP4/ABCC4 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01596
100 μg/vial
Cat # A01596
100 μg/vial
ABCC4 Overview
Facts about Multidrug resistance-associated protein 4.
Multidrug resistance-associated protein 4 (ABCC4)
May be an organic anion pump relevant to cellular detoxification. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ABCC4 |
| Uniprot: | O15439 |
| Entrez: | 10257 |
Family
| Belongs to: |
|---|
| ABC transporter superfamily |
Alternative Names
ABCC4; ATP-binding cassette sub-family C member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; EST170205; MOATB; MOAT-BbA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); MOATBcanalicular multispecific organic anion transporter (ABC superfamily); MRP4; MRP4MRP/cMOAT-related ABC transporter; multidrug resistance-associated protein 4; multispecific organic anion transporter B; Multi-specific organic anion transporter B
Molecular Weight
Mass (kDA):
149.527 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q32.1 |
| Sequence: | 13; NC_000013.11 (95019835..95301451, complement) |
Tissue Specificity
Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.
Subcellular Localizations
Membrane; Multi-pass membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Hiv Infections
- Cholestasis
- Leukemia
- Carcinoma
- Malignant Neoplasm Of Lung
- Injury To Liver
- Liver Carcinoma
- Immunologic Deficiency Syndromes
- Malignant Paraganglionic Neoplasm
- Inflammation
Interacting Proteins
- MPP1
Pathways
- Transport
- Excretion
- Localization
- Secretion
- Drug Resistance
- Drug Transport
- Cell Proliferation
- Pathogenesis
- Urate Transport
- Cgmp Transport
- Intestinal Absorption
- Glomerular Filtration
- Rna Interference
PTMs
- Phosphorylation
- Carboxylation
- Reduction
- Hydroxylation
- Sulphation
- Biotinylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCC4
bosterbio.com/bosterbio-gene-info-cards/ABCC4
References
PMID: 9661885 by Lee K., et al. Isolation of MOAT-B, a widely expressed multidrug resistance- associated protein/canalicular multispecific organic anion transporter-related transporter.
PMID: 12105214 by Adachi M., et al. Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing.
3 Publications of Boster ABCC4 Antibodies & ELISA Kits
- PubMed ID: 10.1155/2021/5566078, The Herbal Constituents in An-Gong-Niu-Huang Wan (AGNH) Protect against Cinnabar...
- PubMed ID: 30105488, Chen L,Liao L,Zhai T,Huang X,Chen Y.Influence of Orally Administered Borneol on ...
- PubMed ID: -, Songsong Wang,Xiao Xiao,Ao Li,Peng Li,"The Herbal Constituents in An-Gong-Niu-Hu...
*More publications can be found for each product on its corresponding product page