Anaphase-promoting complex subunit 1 (Anapc1)

Component of the anaphase promoting complex/cyclosome (APC/C), a mobile cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of'Lys-11'-linked polyubiquitin chains and, to a lesser extent, the formation of'Lys-48'- and'Lys-63'-linked polyubiquitin chains (By similarity).

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