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- Table of Contents
AP-2 complex subunit mu Antibodies
AND AP2M1 ELISA kits, AP-2 complex subunit mu Proteins
Many biological assays use antibodies to detect AP-2 complex subunit mu, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP-2 complex subunit mu in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP-2 complex subunit mu antibodies...
Designing a Western blot for AP-2 complex subunit mu? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AP2M1 Western Blot GuideAP2M1 Infographic by Boster Bio
All AP2M1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06179-3
100 μg/vial
Cat # A06179-3
100 μg/vial
Dog, Human, Monkey, Mouse, Rat
IF, IHC, WB
$523
Cat # M06179-2
100 µl
Cat # M06179-2
100 µl
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A06179-1
0.1 mg
Cat # A06179-1
0.1 mg
Dog, Human, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M06179-1
100 µl
Cat # M06179-1
100 µl
Human, Mouse, Rat
Flow Cytometry, WB
$523
Cat # M06179-3
100 µl
Cat # M06179-3
100 µl
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$405
Cat # A06179-2
100ul
Cat # A06179-2
100ul
AP2M1 Overview
Facts about AP-2 complex subunit mu.
AP-2 complex subunit mu (AP2M1)
Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in various membrane traffic pathways.
Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is included in clathrin-dependent endocytosis where cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) that are destined for fusion with the early endosome.
Gene Information
| Human | |
|---|---|
| Gene Name: | AP2M1 |
| Uniprot: | Q96CW1 |
| Entrez: | 1173 |
Family
| Belongs to: |
|---|
| adaptor complexes medium subunit family |
Alternative Names
Adaptin-mu2; adaptor-related protein complex 2, mu 1 subunit; AP-2 mu chain; Clathrin assembly protein complex 2 medium chain; clathrin coat adaptor protein AP50; Clathrin coat assembly protein AP50; Clathrin coat-associated protein AP50; clathrin-associated/assembly/adaptor protein, medium 1; HA2 50 kDa subunit; KIAA0109; mu subunit; Plasma membrane adaptor AP-2 50 kDa protein; plasma membrane adaptor AP-2 50kDA protein
Molecular Weight
Mass (kDA):
49.655 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q27.1 |
| Sequence: | 3; NC_000003.12 (184174846..184184091) |
Subcellular Localizations
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.
Diseases
- Cystic Fibrosis
- Virus Diseases
- Fibrosis
- Headache
- Hepatitis
- Hepatitis C
Interacting Proteins
- AP2B1
- EGFR
- HIST1H2BC
- RSPH14
- TBC1D5
Pathways
- Secretory Pathway
- Localization
PTMs
Research Areas
- Phospho-Specific
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP2M1
bosterbio.com/bosterbio-gene-info-cards/AP2M1
References
PMID: 12032142 by Geyer M., et al. Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery.
PMID: 14745134 by Nakatsu F., et al. Adaptor protein complexes as the key regulators of protein sorting in the post-Golgi network.