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- Table of Contents
APBA3 Antibodies
AND APBA3 ELISA kits, APBA3 Proteins
Many biological assays use antibodies to detect APBA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with APBA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop APBA3 antibodies...
Designing a Western blot for APBA3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the APBA3 Western Blot GuideAPBA3 Infographic by Boster Bio
All APBA3 Products
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Applications
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APBA3 Overview
Facts about Amyloid-beta A4 precursor protein-binding family A member 3.
Amyloid-beta A4 precursor protein-binding family A member 3 (APBA3)
May modulate processing of the amyloid-beta precursor protein (APP) and hence creation of APP-beta. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | APBA3 |
| Uniprot: | O96018 |
| Entrez: | 9546 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Adapter protein X11gamma; amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2); amyloid beta (A4) precursor protein-binding, family A, member 3; APBA3; MGC:15815; MINT3; mint-3; Neuronal Munc18-1-interacting protein 3; Neuron-specific X11L2 protein; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; X11L2; X11L2amyloid beta A4 precursor protein-binding family A member 3; X11-like 2 protein
Molecular Weight
Mass (kDA):
61.454 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (3750772..3761696, complement) |
Tissue Specificity
Expressed in all tissues examined with lower levels in brain and testis.
Subcellular Localizations
Cytoplasm, perinuclear region.
Diseases
- Alzheimer's Disease
- Malignant Neoplasms
- Neoplasms
- Microsatellite Instability
- Rectal Neoplasms
- Colonic Neoplasms
- Malignant Tumor Of Colon
- Hypoxia
- Carcinoma
- Braf Np_004324.2:p.v600e
- Neuroblastoma
- Cell Transformation, Neoplastic
- Rectal Carcinoma
Interacting Proteins
- Azi2
- HIF1AN
- NECAB3
- TANK
- TBKBP1
Pathways
- Localization
- Methylation
- Glycolysis
- Transport
- Secretory Pathway
- Endocytosis
- Oxidative Phosphorylation
- Pathogenesis
- Secretion
- Dna Methylation
- Vesicle Fusion
PTMs
- Methylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APBA3
bosterbio.com/bosterbio-gene-info-cards/APBA3
References
PMID: 10049767 by Tanahashi H., et al. X11L2, a new member of X11 protein family interacts with Alzheimer's beta-amyloid precursor protein.
PMID: 10574372 by Tanahashi H., et al. Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein.