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- Table of Contents
Aquaporin-5 Antibodies
AND AQP5 ELISA kits, Aquaporin-5 Proteins
Many biological assays use antibodies to detect Aquaporin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Aquaporin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Aquaporin-5 antibodies...
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AQP5 Infographic by Boster Bio
All AQP5 Products
Product
Figures
Specificity
Applications
Price
Anti-Aquaporin 5/AQP5 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # A03085
100 μg/vial
Cat # A03085
100 μg/vial
AQP5 Overview
Facts about Aquaporin-5.
Aquaporin-5 (AQP5)
Types a water-specific channel. Implicated in the creation of saliva, tears, and pulmonary secretions.
Required for TRPV4 activation by hypotonicity (PubMed:16571723). Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723).
Gene Information
| Human | |
|---|---|
| Gene Name: | AQP5 |
| Uniprot: | P55064 |
| Entrez: | 362 |
Family
| Belongs to: |
|---|
| MIP/aquaporin (TC 1.A.8) family |
Alternative Names
AQP-5; aquaporin 5; aquaporin-5
Molecular Weight
Mass (kDA):
28.292 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.12 |
| Sequence: | 12; NC_000012.12 (49961855..49965682) |
Subcellular Localizations
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane.
Diseases
- Salivary Gland Diseases
- Edema
- Lung Injury
- Sjogren's Syndrome
- Malignant Neoplasms
- Inflammation
- Neoplasms
- Corneal Diseases
- Pulmonary Edema
- Xerostomia
- Acute Lung Injury
- Neoplasm Metastasis
Interacting Proteins
- HNRNPK
- KRT31
- KRT40
- MDFI
- NOTCH2NL
Pathways
- Transport
- Secretion
- Localization
- Water Transport
- Fluid Transport
- Water Homeostasis
- Cell Proliferation
- Pathogenesis
- Lung Development
- Saliva Secretion
- Cell Differentiation
- Cell Migration
- Cellular Localization
PTMs
- Phosphorylation
- Cleavage
- Demethylation
- Methylation
Research Areas
- Cancer
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AQP5
bosterbio.com/bosterbio-gene-info-cards/AQP5
References
PMID: 8621489 by Lee M.D., et al. The human aquaporin-5 gene. Molecular characterization and chromosomal localization.
PMID: 16571723 by Liu X., et al. A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.
5 Publications of Boster Aquaporin-5 Antibodies & ELISA Kits
- PubMed ID: 10.1080/09291016.2021.2007329, Expression of AQP1, AQP3, AQP4 and AQP5 in upper respiratory tract of buffaloes ...
- PubMed ID: 10.1016/j.ydbio.2017.07.018, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular matur...
- PubMed ID: 10.1016/j.jtherbio.2020.102727, Seasonal effect in expression of AQP1, AQP3 and AQP5 in skin of Murrah buffaloes
- PubMed ID: 26668595, Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by sti...
- PubMed ID: 28811219, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular matur...
*More publications can be found for each product on its corresponding product page