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- Table of Contents
ARHGEF7 Antibodies
AND ARHGEF7 ELISA kits, ARHGEF7 Proteins
Many biological assays use antibodies to detect ARHGEF7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGEF7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGEF7 antibodies...
Designing an IHC experiment for ARHGEF7? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ARHGEF7 IHC GuideARHGEF7 Infographic by Boster Bio
All ARHGEF7 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02764-2
100 µg/vial
Cat # A02764-2
100 µg/vial
Human, Mouse, Rat
ELISA
$540
Cat # EKC2576
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2576
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2575
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2575
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2170
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2170
1 kit, containing two 96-well plates and all necessary reagents
ARHGEF7 Overview
Facts about Rho guanine nucleotide exchange factor 7.
Rho guanine nucleotide exchange factor 7 (ARHGEF7)
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading.
Promotes targeting of RAC1 to focal adhesions (By similarity). May be a positive regulator of apoptosis.
Gene Information
| Human | |
|---|---|
| Gene Name: | ARHGEF7 |
| Uniprot: | Q14155 |
| Entrez: | 8874 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Beta-Pix; COOL1COOL-1; DKFZp686C12170; DKFZp761K1021; guanine nucleotide exchange factor 7; KIAA0142KIAA0412; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPRBETA-PIX; PAK3; PAK3BP; PIXBPAK-interacting exchange factor beta; Rho guanine nucleotide exchange factor (GEF) 7; rho guanine nucleotide exchange factor 7; SH3 domain-containing proline-rich protein
Molecular Weight
Mass (kDA):
90.012 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q34 |
| Sequence: | 13; NC_000013.11 (111114619..111305734) |
Subcellular Localizations
Cell junction, focal adhesion. Cell projection, ruffle. Cytoplasm, cell cortex. Cell projection, lamellipodium. Detected at cell adhesions. A small proportion is detected at focal adhesions.
Diseases
- Tissue Adhesions
- Neoplasms
- Penoscrotal Transposition
- Neoplasm Metastasis
- Microcephaly
- Colonic Neoplasms
- Malignant Tumor Of Colon
- Malignant Paraganglionic Neoplasm
- Carcinoma
- Chromosome 13 Ring
Interacting Proteins
- CBL
- GIT1
- LRRK2
- MEOX2
- NAA10
- PAK1
- PAK2
- PPP2R1A
- RAC1
- SCRIB
Pathways
- Cell Adhesion
- Cell Migration
- Transposition
- Mitosis
- Pathogenesis
- Anaphase
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGEF7
bosterbio.com/bosterbio-gene-info-cards/ARHGEF7
References
PMID: 9726964 by Bagrodia S., et al. A novel regulator of p21-activated kinases.
PMID: 15491607 by Homma K., et al. Alternative splice variants encoding unstable protein domains exist in the human brain.