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- Table of Contents
ATF1 Antibodies
AND ATF1 ELISA kits, ATF1 Proteins
Many biological assays use antibodies to detect ATF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATF1 antibodies...
Designing a Western blot for ATF1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ATF1 Western Blot GuideATF1 Infographic by Boster Bio
All ATF1 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01600-1
100 μg/vial
Cat # M01600-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PB9130
100 μg/vial
Cat # PB9130
100 μg/vial
Human, Mouse
ELISA
$540
Cat # EKC2019
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2019
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1040
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1040
1 kit, containing one 96-well plate and all necessary reagents
Human
Cell Culture
$77
Cat # PROTP39905-3
5ug,20ug,100ug
Cat # PROTP39905-3
5ug,20ug,100ug
ATF1 Overview
Facts about Cyclic AMP-dependent transcription factor ATF-1.
Cyclic AMP-dependent transcription factor ATF-1 (ATF1)
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I.
Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 along with other antioxidant detoxification genes.
Gene Information
| Human | |
|---|---|
| Gene Name: | ATF1 |
| Uniprot: | P18846 |
| Entrez: | 466 |
Family
| Belongs to: |
|---|
| bZIP family |
Alternative Names
activating transcription factor 1FUS/ATF-1; ATF1; cAMP-dependent transcription factor ATF-1; EWS-ATF1; Protein TREB36; TREB36; TREB36cyclic AMP-dependent transcription factor ATF-1
Molecular Weight
Mass (kDA):
29.233 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.12 |
| Sequence: | 12; NC_000012.12 (50763682..50821162) |
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Sarcoma
- Sarcoma, Clear Cell
- Melanoma
- Malignant Neoplasms
- Malignant Paraganglionic Neoplasm
- Soft Tissue Neoplasms
- Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
- Physiological Stress
- Chromosomal Translocation
- Neoplasm Metastasis
- Leukemia
Interacting Proteins
- CREB1
- ESR1
- JUN
- NFATC1
- NFIL3
Pathways
- Cell Cycle
- Fermentation
- Localization
- Translation
- Response To Oxidative Stress
- Meiosis
- Methylation
- Mating
- Cell Proliferation
- Hypersensitivity
- Cell Death
- Mapk Cascade
- Heterochromatin Assembly
PTMs
- Phosphorylation
- Acetylation
- Methylation
- Deacetylation
- Dephosphorylation
Research Areas
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATF1
bosterbio.com/bosterbio-gene-info-cards/ATF1
References
PMID: 2196176 by Yoshimura T., et al. Multiple cDNA clones encoding nuclear proteins that bind to the tax- dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.
PMID: 1655749 by Rehfuss R.P., et al. The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A.