This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Aminopeptidase N Antibodies
AND ANPEP ELISA kits, Aminopeptidase N Proteins
Many biological assays use antibodies to detect Aminopeptidase N, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Aminopeptidase N in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Aminopeptidase N antibodies...
Previous: A1BG
Next: SLC25A4
ANPEP Infographic by Boster Bio
All ANPEP Products
Product
Figures
Specificity
Applications
Price
Human CD13/Aminopeptidase N ELISA Kit PicoKine®
3 Citations 4 Q&As
Human
ELISA
$499
Cat # EK1216
96 wells/kit, with removable strips.
Cat # EK1216
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1222
96 wells/kit, with removable strips.
Cat # EK1222
96 wells/kit, with removable strips.
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M02591
100 μl
Cat # M02591
100 μl
Anti-CD13/ANPEP Picoband® Antibody
3 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A02591-2
100 μg/vial
Cat # A02591-2
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, WB
$370
Cat # A02591-3
100 μg/vial
Cat # A02591-3
100 μg/vial
Enzyme Activity, SDS-PAGE
$293
Cat # PROTP97449
Starting from 10ug
Cat # PROTP97449
Starting from 10ug
Human, Monkey, Rat
IHC, WB
$370
Cat # M02591-4
100 μg/vial
Cat # M02591-4
100 μg/vial
Human, Monkey, Rat
IHC, WB
$370
Cat # M02591-5
100 μg/vial
Cat # M02591-5
100 μg/vial
Human, Monkey, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M02591-6
100 μg/vial
Cat # M02591-6
100 μg/vial
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M02591-7
100 μl/vial
Cat # M02591-7
100 μl/vial
ANPEP Overview
Facts about Aminopeptidase N.
Aminopeptidase N (ANPEP)
Broad specificity aminopeptidase which plays a part in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides such as peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines.
May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization.
Gene Information
| Human | |
|---|---|
| Gene Name: | ANPEP |
| Uniprot: | P15144 |
| Entrez: | 290 |
Family
| Belongs to: |
|---|
| peptidase M1 family |
Alternative Names
alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; EC 3.4.11; EC 3.4.11.2; gp150; LAP1; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; p150; PEPN; PEPNhAPN
Molecular Weight
Mass (kDA):
109.54 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q26.1 |
| Sequence: | 15; NC_000015.10 (89784895..89814852, complement) |
Tissue Specificity
Expressed in epithelial cells of the kidney, intestine, and respiratory tract; granulocytes, monocytes, fibroblasts, endothelial cells, cerebral pericytes at the blood- brain barrier, synaptic membranes of cells in the CNS. Also expressed in endometrial stromal cells, but not in the endometrial glandular cells. Found in the vasculature of tissues that undergo angiogenesis and in malignant gliomas and lymph node metastases from multiple tumor types but not in blood vessels of normal tissues. A soluble form has been found in plasma. It is found to be elevated in plasma and effusions of cancer patients.
Subcellular Localizations
Cell membrane; Single-pass type II membrane protein. Also found as a soluble form.
Diseases
- Malignant Neoplasms
- Neoplasms
- Hypertensive Disease
- Tumor Angiogenesis
- Adenocarcinoma
- Severe Acute Respiratory Syndrome
- Prostatic Neoplasms
- Cell Invasion
- Malignant Neoplasm Of Prostate
- Neoplasm Metastasis
- Meningeal Disorder
- Viral Meningitis
- Neoplasm Invasiveness
Pathways
- Localization
- Angiogenesis
- Reverse Transcription
- Coagulation
- Translation
- Immune Response
- Pathogenesis
PTMs
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANPEP
bosterbio.com/bosterbio-gene-info-cards/ANPEP
References
PMID: 2901990 by Olsen J., et al. Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA.
PMID: 2564851 by Look A.T., et al. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N.
6 Publications of Boster Aminopeptidase N Antibodies & ELISA Kits
- PubMed ID: 10.1021/acs.analchem.7b00021, Ultrasensitive Detection of Aminopeptidase N Activity in Urine and Cells with a ...
- PubMed ID: 10.1016/j.cellsig.2021.110168, Mechanism of neutrophil extracellular traps generation and their role in trophob...
- PubMed ID: -, Yan,Q.,Wang,L.,Song,F.et al.Effects of QDs@Gd3+-NGR on targeted fluorescence-mag...
- PubMed ID: 28230342, Ultrasensitive detection of aminopeptidase N activity in urine and cells with a ...
- PubMed ID: 26616638, Isolation and morphological characterization of ovine amniotic fluid mesenchymal...
- PubMed ID: 24681123, Wang Y, Li Jr, Sun Mx, Ni B, Huan C, Huang L, Li C, Fan Hj, Ren Xf, Mao X. Antiv...
*More publications can be found for each product on its corresponding product page