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- Table of Contents
Aquaporin-5 Antibodies
AND AQP5 ELISA kits, Aquaporin-5 Proteins
Many biological assays use antibodies to detect Aquaporin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Aquaporin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Aquaporin-5 antibodies...
Designing a Western blot for Aquaporin-5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AQP5 Western Blot GuideAQP5 Infographic by Boster Bio
All AQP5 Products
Product
Figures
Specificity
Applications
Price
Anti-Aquaporin 5/AQP5 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # A03085
100 μg/vial
Cat # A03085
100 μg/vial
AQP5 Overview
Facts about Aquaporin-5.
Aquaporin-5 (AQP5)
Types a water-specific channel. Implicated in the creation of saliva, tears, and pulmonary secretions.
Required for TRPV4 activation by hypotonicity (PubMed:16571723). Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723).
Gene Information
| Human | |
|---|---|
| Gene Name: | AQP5 |
| Uniprot: | P55064 |
| Entrez: | 362 |
Family
| Belongs to: |
|---|
| MIP/aquaporin (TC 1.A.8) family |
Alternative Names
AQP-5; aquaporin 5; aquaporin-5
Molecular Weight
Mass (kDA):
28.292 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.12 |
| Sequence: | 12; NC_000012.12 (49961855..49965682) |
Subcellular Localizations
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane.
Diseases
- Salivary Gland Diseases
- Edema
- Lung Injury
- Sjogren's Syndrome
- Malignant Neoplasms
- Inflammation
- Neoplasms
- Corneal Diseases
- Pulmonary Edema
- Xerostomia
- Acute Lung Injury
- Neoplasm Metastasis
Interacting Proteins
- HNRNPK
- KRT31
- KRT40
- MDFI
- NOTCH2NL
Pathways
- Transport
- Secretion
- Localization
- Water Transport
- Fluid Transport
- Water Homeostasis
- Cell Proliferation
- Pathogenesis
- Lung Development
- Saliva Secretion
- Cell Differentiation
- Cell Migration
- Cellular Localization
PTMs
- Phosphorylation
- Cleavage
- Demethylation
- Methylation
Research Areas
- Cancer
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AQP5
bosterbio.com/bosterbio-gene-info-cards/AQP5
References
PMID: 8621489 by Lee M.D., et al. The human aquaporin-5 gene. Molecular characterization and chromosomal localization.
PMID: 16571723 by Liu X., et al. A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.
5 Publications of Boster Aquaporin-5 Antibodies & ELISA Kits
- PubMed ID: 10.1080/09291016.2021.2007329, Expression of AQP1, AQP3, AQP4 and AQP5 in upper respiratory tract of buffaloes ...
- PubMed ID: 10.1016/j.ydbio.2017.07.018, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular matur...
- PubMed ID: 10.1016/j.jtherbio.2020.102727, Seasonal effect in expression of AQP1, AQP3 and AQP5 in skin of Murrah buffaloes
- PubMed ID: 26668595, Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by sti...
- PubMed ID: 28811219, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular matur...
*More publications can be found for each product on its corresponding product page