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- Table of Contents
C1S Antibodies
AND C1S ELISA kits, C1S Proteins
Many biological assays use antibodies to detect C1S, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C1S in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C1S antibodies...
Designing a Western blot for C1S? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the C1S Western Blot GuideC1S Infographic by Boster Bio
All C1S Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1393
96 wells/kit, with removable strips.
Cat # EK1393
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1393
96 wells/kit, with removable strips.
Cat # FEK1393
96 wells/kit, with removable strips.
Human, Mouse, Rat
IHC, IHC-F, ICC, WB
$370
Cat # PA1897
100 μg/vial
Cat # PA1897
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02057-4
100 μg
Cat # M02057-4
100 μg
Human, Mouse, Rat
ELISA
$540
Cat # EKC1954
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1954
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1953
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1953
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1519
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1519
1 kit, containing one 96-well plate and all necessary reagents
C1S Overview
Facts about Complement C1s subcomponent.
Complement C1s subcomponent (C1S)
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, trigger C2 and C4.
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Gene Information
| Human | |
|---|---|
| Gene Name: | C1S |
| Uniprot: | P09871 |
| Entrez: | 716 |
Family
| Belongs to: |
|---|
| peptidase S1 family |
Alternative Names
basic proline-rich peptide IB-1; C1 esterase; C1S; complement C1s subcomponent; Complement component 1 subcomponent s; complement component 1, s subcomponent; Complement Component C1s; EC 3.4.21; EC 3.4.21.42; FLJ44757
Molecular Weight
Mass (kDA):
76.684 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p13.31 |
| Sequence: | 12; NC_000012.12 (7060718..7071032) |
Diseases
- Hemolysis (disorder)
- Angioedema
- Lupus Erythematosus, Systemic
- Inflammation
- Angioedemas, Hereditary
- Edema
- Rheumatoid Arthritis
- Arthritis
- Infective Disorder
- Tissue Adhesions
- Glomerulonephritis
- Neoplasms
- Immunologic Deficiency Syndromes
Interacting Proteins
- C1R
Pathways
- Complement Activation
- Coagulation
- Proteolysis
- Secretion
- Pathogenesis
- Localization
- Glycosylation
- Immune Response
- Phagocytosis
- Cell Proliferation
- Opsonization
- Fibrinolysis
- Platelet Aggregation
PTMs
- Cleavage
- Glycosylation
- Phosphorylation
- Iodination
- Hydroxylation
- Acylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C1S
bosterbio.com/bosterbio-gene-info-cards/C1S
References
PMID: 3500856 by McKinnon C.M., et al. Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence.
PMID: 2831944 by Tosi M., et al. Complete cDNA sequence of human complement Cls and close physical linkage of the homologous genes Cls and Clr.