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- Table of Contents
2 Citations 17 Q&As
2 Citations 4 Q&As
1 Citations 4 Q&As
Facts about Calpain-1 catalytic subunit.
Human | |
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Gene Name: | CAPN1 |
Uniprot: | P07384 |
Entrez: | 823 |
Belongs to: |
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peptidase C2 family |
Calcium-activated neutral proteinase 1; calpain 1, (mu/I) large subunit; Calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; CANP 1; CANP; CANPL1EC 3.4.22.52; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; EC 3.4.22; micromolar-calpain; muCANPCANP1; muCL
Mass (kDA):
81.89 kDA
Human | |
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Location: | 11q13.1 |
Sequence: | 11; NC_000011.10 (65181373..65212006) |
Ubiquitous.
Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding. In granular keratinocytes and in lower corneocytes, colocalizes with FLG and FLG2 (PubMed:21531719).
PMID: 3017764 by Aoki K., et al. Complete amino acid sequence of the large subunit of the low-Ca2+- requiring form of human Ca2+-activated neutral protease (muCANP) deduced from its cDNA sequence.
PMID: 2400579 by Sorimachi H., et al. A novel member of the calcium-dependent cysteine protease family.
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