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- Table of Contents
CAPN1 Antibodies
AND CAPN1 ELISA kits, CAPN1 Proteins
Many biological assays use antibodies to detect CAPN1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAPN1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAPN1 antibodies...
Designing a Western blot for CAPN1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CAPN1 Western Blot GuideCAPN1 Infographic by Boster Bio
All CAPN1 Products
Product
Figures
Specificity
Applications
Price
Anti-Calpain 1/CAPN1 Antibody Picoband®
4 Citations
Human, Mouse, Rat
IF, IHC, IHC-F, ICC, WB
$370
Cat # PA1364
100 μg/vial
Cat # PA1364
100 μg/vial
Anti-Calpain 1/CAPN1 Antibody Picoband®
2 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9330
100 μg/vial
Cat # PB9330
100 μg/vial
Human
Flow Cytometry, WB
$370
Cat # M01943-4
100 μg/vial
Cat # M01943-4
100 μg/vial
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M01943-3
100 μg/vial
Cat # M01943-3
100 μg/vial
Anti-Calpain 1 CAPN1 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01943
100 μl
Cat # M01943
100 μl
Human
$960
Cat # LS440854
20 µg, 100 µg
Cat # LS440854
20 µg, 100 µg
CAPN1 Overview
Facts about Calpain-1 catalytic subunit.
Calpain-1 catalytic subunit (CAPN1)
Calcium-regulated non-lysosomal thiol-protease that catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CAPN1 |
| Uniprot: | P07384 |
| Entrez: | 823 |
Family
| Belongs to: |
|---|
| peptidase C2 family |
Alternative Names
Calcium-activated neutral proteinase 1; calpain 1, (mu/I) large subunit; Calpain mu-type; calpain, large polypeptide L1; calpain-1 catalytic subunit; Calpain-1 large subunit; CANP 1; CANP; CANPL1EC 3.4.22.52; Cell proliferation-inducing gene 30 protein; cell proliferation-inducing protein 30; EC 3.4.22; micromolar-calpain; muCANPCANP1; muCL
Molecular Weight
Mass (kDA):
81.89 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.1 |
| Sequence: | 11; NC_000011.10 (65181373..65212006) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding. In granular keratinocytes and in lower corneocytes, colocalizes with FLG and FLG2 (PubMed:21531719).
Diseases
- Sore To Touch
- Neoplasms
- Cholangiocarcinoma
- Malignant Neoplasms
- Nerve Degeneration
- Tissue Adhesions
- Alzheimer's Disease
- Malaria
- Endocrine Gland Neoplasms
- Infarction
- Multiple Endocrine Neoplasia Type 1
- Multiple Endocrine Neoplasia
Interacting Proteins
- EZR
- PTPN1
- STAT3
Pathways
- Cell Death
- Proteolysis
- Aging
- Cell Migration
- Pathogenesis
- Cell Adhesion
- Hyperphosphorylation
- Localization
- Autophagy
- Secretion
- Cell Motility
- Cell Differentiation
- Cell Proliferation
PTMs
- Cleavage
- Phosphorylation
- Oxidation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPN1
bosterbio.com/bosterbio-gene-info-cards/CAPN1
References
PMID: 3017764 by Aoki K., et al. Complete amino acid sequence of the large subunit of the low-Ca2+- requiring form of human Ca2+-activated neutral protease (muCANP) deduced from its cDNA sequence.
PMID: 2400579 by Sorimachi H., et al. A novel member of the calcium-dependent cysteine protease family.
3 Publications of Boster CAPN1 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.cyto.2017.04.007, Determination of cytokine levels in multiple sclerosis patients and their releva...
- PubMed ID: 21185840, Mo Xg, Chen Qw, Li Xs, Zheng Mm, Ke Dz, Deng W, Li Gq, Jiang J, Wu Zq, Wang L, W...
- PubMed ID: 25415668, Chen Hx, Tang Sp, Gao Ft, Xu Jl, Jiang Xp, Cao J, Fu Gb, Sun K, Liu Sz, Shi W. M...
*More publications can be found for each product on its corresponding product page