Cholecystokinin Antibodies

AND CCK ELISA kits, Cholecystokinin Proteins

Many biological assays use antibodies to detect Cholecystokinin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cholecystokinin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cholecystokinin antibodies...

We validate the specificity of these antibodies to Cholecystokinin by testing them on tissues known to express CCK positively and negatively. Browse below to find the CCK antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCK Infographic by Boster Bio

All CCK Products

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Anti-CCK (V46) Antibody

Immunohistochemistry (IHC) analyzes of CCK (V46) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50

Human, Mouse, Rat

IHC

$405
Cat # A01098
100ul

CCK Overview

Facts about Cholecystokinin.

CCK 3D structure. Source: alphafold

Cholecystokinin (CCK)

This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its role in the brain is not clear.

Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. .

Gene Information

Human
Gene Name:	CCK
Uniprot:	P06307
Entrez:	885

Family

Belongs to:

gastrin/cholecystokinin family

Alternative Names

cholecystokinin; MGC117187

Molecular Weight

Mass (kDA):
12.669 kDA

Genomic Context


Human

Location:	3p22.1
Sequence:	3; NC_000003.12 (42257824..42266185, complement)

Subcellular Localizations

Secreted.

Diseases

Nervousness
Pancreatitis
Obesity
Pain
Neoplasms
Malignant Neoplasms
Anxiety Disorders
Acute Pancreatitis
Pancreatic Neoplasm
Pathologic Fistula
Pituitary Diseases
Pathological Dilatation

Cholecystolithiasis
Carcinoma
Malignant Neoplasm Of Pancreas
Diabetes Mellitus
Hyperplasia
Gall Bladder Diseases

Interacting Proteins

CCKBR

Pathways

Secretion
Gastric Emptying
Acid Secretion
Localization
Gastric Acid Secretion
Protein Secretion
Pathogenesis
Reflex
Cell Proliferation
Feeding Behavior
Innervation
Insulin Secretion
Transport

Cell Growth
Gastric Motility
Hormone Secretion
Exocytosis
Regeneration
Aging
Gallstone Formation

PTMs

Phosphorylation
Sulphation
Cleavage
Amidation
Reduction
Iodination
Oxidation
Glycosylation
Dephosphorylation
Deglycosylation

Methylation
Ribosylation
Acylation
Biotinylation
Deamidation
Nitration
Carboxylation
Deamination
Ubiquitination
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCK

References

PMID: 3856870 by Takahashi Y., et al. Molecular cloning of the human cholecystokinin gene by use of a synthetic probe containing deoxyinosine.

PMID: 11076522 by Vishnuvardhan D., et al. Role of tyrosine sulfation and serine phosphorylation in the processing of procholecystokinin to amidated cholecystokinin and its secretion in transfected AtT-20 cells.