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- Table of Contents
CCT8 Antibodies
AND CCT8 ELISA kits, CCT8 Proteins
Many biological assays use antibodies to detect CCT8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CCT8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CCT8 antibodies...
Designing a Western blot for CCT8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CCT8 Western Blot GuideDesigning an IHC experiment for CCT8? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CCT8 IHC GuideCCT8 Infographic by Boster Bio
All CCT8 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9993
100 μg/vial
Cat # PB9993
100 μg/vial
CCT8 Overview
Facts about T-complex protein 1 subunit theta.
T-complex protein 1 subunit theta (CCT8)
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Gene Information
| Human | |
|---|---|
| Gene Name: | CCT8 |
| Uniprot: | P50990 |
| Entrez: | 10694 |
Family
| Belongs to: |
|---|
| TCP-1 chaperonin family |
Alternative Names
C21orf112; Cctq; CCT-theta; chaperonin containing TCP1, subunit 8 (theta); chromosome 21 open reading frame 112; D21S246; KIAA0002; PRED71; T-complex protein 1 subunit theta; T-complex protein 1, theta subunit, 10Renal carcinoma antigen NY-REN-15; TCP-1-theta
Molecular Weight
Mass (kDA):
59.621 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q21.3 |
| Sequence: | 21; NC_000021.9 (29056322..29073797, complement) |
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Diseases
- Down Syndrome
- Periodontitis
- Tetraploidy
- Mycoses
Interacting Proteins
- TCP1
Pathways
- Ribosome Biogenesis
- Transport
- Cell Activation
- Sperm Capacitation
- Protein Folding
- T Cell Activation
- Meristem Maintenance
- Cell Differentiation
PTMs
- Acetylation
- Isopeptide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCT8
bosterbio.com/bosterbio-gene-info-cards/CCT8
References
PMID: 8590283 by Yamazaki M., et al. Nucleotide sequence surrounding the locus marker D21S246 on human chromosome 21.
PMID: 7890169 by Kubota H., et al. The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1.