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- Table of Contents
CD164 Antibodies
AND CD164 ELISA kits, CD164 Proteins
Many biological assays use antibodies to detect CD164, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD164 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD164 antibodies...
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CD164 Infographic by Boster Bio
All CD164 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$750
Cat # EK1811
96 wells/kit, with removable strips.
Cat # EK1811
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, IF, IHC
$380
Cat # A05879
100ul
Cat # A05879
100ul
Human
ELISA
$499
Cat # FEK1811
96 wells/kit, with removable strips.
Cat # FEK1811
96 wells/kit, with removable strips.
CD164 Overview
Facts about Sialomucin core protein 24.
Sialomucin core protein 24 (CD164)
Sialomucin that may play an integral role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis.
May play an essential role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility.
Gene Information
| Human | |
|---|---|
| Gene Name: | CD164 |
| Uniprot: | Q04900 |
| Entrez: | 8763 |
Family
| Belongs to: |
|---|
| CD164 family |
Alternative Names
CD164 antigen; CD164 molecule, sialomucin; CD164; Endolyn; MGC-24; MGC-24v; MUC-24; Multi-glycosylated core protein 24; sialomucin
Molecular Weight
Mass (kDA):
20.917 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q21 |
| Sequence: | 6; NC_000006.12 (109366514..109382812, complement) |
Tissue Specificity
Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells.
Subcellular Localizations
Lysosome membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Diseases
- Tissue Adhesions
- Carcinoma
- Malignant Neoplasms
- Neoplasm Metastasis
- Neoplasms
- Allergy
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Stomach
- Prostatic Neoplasms
- Hay Fever
- Colorectal Cancer
- Malignant Neoplasm Of Prostate
- Cell Invasion
Interacting Proteins
- CXCR4
- NOTCH2NL
Pathways
- Cell Proliferation
- Cell Adhesion
- Glycosylation
- Localization
- Cell Growth
- Basophil Activation
- Leukocyte Differentiation
- Regeneration
- Secretion
- Cell Migration
- Cell Motility
- Myoblast Fusion
- Regulation Of Cell Adhesion
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD164
bosterbio.com/bosterbio-gene-info-cards/CD164
References
PMID: 1478919 by Masuzawa Y., et al. A novel core protein as well as polymorphic epithelial mucin carry peanut agglutinin binding sites in human gastric carcinoma cells: sequence analysis and examination of gene expression.
PMID: 9763543 by Zannettino A.C.W., et al. The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis.