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- Table of Contents
Facts about Sialomucin core protein 24.
May play an essential role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility.
Human | |
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Gene Name: | CD164 |
Uniprot: | Q04900 |
Entrez: | 8763 |
Belongs to: |
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CD164 family |
CD164 antigen; CD164 molecule, sialomucin; CD164; Endolyn; MGC-24; MGC-24v; MUC-24; Multi-glycosylated core protein 24; sialomucin
Mass (kDA):
20.917 kDA
Human | |
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Location: | 6q21 |
Sequence: | 6; NC_000006.12 (109366514..109382812, complement) |
Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells.
Lysosome membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Boster Bio has a monoclonal antibody that is high-quality for CD164. This product is suitable for scientists from all over the world. Scientists of all disciplines can submit their results for species and applications. Boster scientists can get product credits. Boster products provide benefits that are comparable to using a commercial product. Boster Bio Anti -Hu CD164 Monoclonal Purified Antibody.
The Boster Bio Anti-Hu CD164 Purized Monoclonal ELISA kit has been validated for use with a range of samples, including tissue homogenates and cells. Tissue homogenates are not routinely valid for ELISA testing. In such cases, samples should be collected on the spot and aliquoted into single-use volumes. Store at -20°C. Repeat freeze-thaw cycles will limit protein degradation.
Boster Bio Anti-Hu CD164 Pure Monoclonal ELISA kits is a highly sensitive and precise immunohistochemical test. It detects the expression of the antigen in cells and tissues. The antigen is a member of the family of antibodies called cytokeratins. These antibodies are important in the pathogenesis and treatment of febrile transfusion reactions, drug induced neutropenia, autoimmune neutropenia, as well as drug-induced neutropenia. Flow cytometry is the best way to detect and quantify them.
It is important to compare the recombinant antibody preparations with those that were previously available. The spindle can be labeled with fragments from Hec1 scFvC, FabAlexa 647 and rMAb. Double staining may also prove useful with a full-length antigen. Moreover, rMAbpMELT recognizes endogenous proteins and can be used to detect exogenously expressed KNL1.
Recombinant antibody preparations offer several advantages over traditional antibodies. They are more reproducible, are less harmful to animals, are more versatile, and are easier to use. They are also more sensitive against a wide range epitopes and sequences. They are compatible for immunoblotting using the 3F3/2 Epitope. These are a great choice when you want to be confident in the safety and efficacy reagents.
Human CD164 (MUC-24), a member of C-X-C chemokine-receptor family. Its gene map to 6q21. It can be expressed in many cell types such as monocytes and T-cells. Its functions could include controlling muscle development. Other than MGC-24, human CD164 has been associated with various disorders such as Sezary syndrome and impaired listening.
Human immunoglobulin G antibodies undergo affinity maturation. This occurs when the genes encoding variable regions of antibodies undergosomal hypermutation to increase the affinity for antigens. IgM antibodies produce immunoglobulin G antibody, which are more specific and less heterogeneous than the IgM antibodies. The DNA icosahedral structure of the virus in African swine fever is what makes it so deadly. The development and maintenance of neutralizing antibodies are part of this protective immunity.
The CD164 ELISA kit includes 20 negative controls with a sensitivity value of 50pg/ml. This sensitivity is calculated by adding 20 negative controls to the total, plus two standard deviations. The experimental dilution rates for any given sample are the dilutions from the linear portion of the curve. This monoclonal antibody can be used in many different ways.
Since 1972, Bethyl laboratory has been a leader in antibody production. Their commitment to quality and personal service ensure that their products meet the highest standards. They have extensive experience in producing monoclonal antibodies and have received the highest honors for their work. Boster Bio AntiHu CD164 Purified Monoclonal Antibody is a reliable choice if you are looking to find a reliable antibody.
Boster Bio Anti-Hu CD164 Pure Monoclonal Antibody identifies specific antibodies that are reactive with human Leukocytes. It recognizes antibodies from blood groups and antigens of human leukocytes. Boster Bio AntiHu CD164 Purified Monoclonal antibody is one of the most widely used anti-Hu antibodies on the market.
PMID: 1478919 by Masuzawa Y., et al. A novel core protein as well as polymorphic epithelial mucin carry peanut agglutinin binding sites in human gastric carcinoma cells: sequence analysis and examination of gene expression.
PMID: 9763543 by Zannettino A.C.W., et al. The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis.