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- Table of Contents
Endosialin Antibodies
AND CD248 ELISA kits, Endosialin Proteins
Many biological assays use antibodies to detect Endosialin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endosialin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endosialin antibodies...
Designing a Western blot for Endosialin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD248 Western Blot GuideDesigning an IHC experiment for Endosialin? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CD248 IHC GuideCD248 Infographic by Boster Bio
All CD248 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M04735-1
100 μg
Cat # M04735-1
100 μg
CD248 Overview
Facts about Endosialin.
Endosialin (CD248)
May play a role in tumor angiogenesis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CD248 |
| Uniprot: | Q9HCU0 |
| Entrez: | 57124 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
2610111G01Rik; CD164 sialomucin-like 1; CD164L1; CD248 antigen; CD248 antigen, endosialin; CD248 molecule, endosialin; CD248; Endosialin; MGC119479; TEM1; TEM1MGC119478; Tumor endothelial marker 1
Molecular Weight
Mass (kDA):
80.859 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.2 |
| Sequence: | 11; NC_000011.10 (66314494..66317044, complement) |
Tissue Specificity
Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Neoplasms
- Malignant Neoplasms
- Tumor Angiogenesis
- Pathologic Neovascularization
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Inflammation
- Tissue Adhesions
- Neoplasm Metastasis
- Sarcoma
- Arthritis
- Tumor Progression
Pathways
- Angiogenesis
- Cell Adhesion
- Tube Formation
- Localization
- Cell Proliferation
- Tissue Development
- Fibroblast Activation
- Sprouting Angiogenesis
- Blood Coagulation
- Blood Vessel Development
- Vasculature Development
- Inflammatory Response
- Senescence
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD248
bosterbio.com/bosterbio-gene-info-cards/CD248
References
PMID: 10947988 by St Croix B., et al. Genes expressed in human tumor endothelium.
PMID: 11084048 by Christian S., et al. Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium.