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Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). .
|Sequence:||19; NC_000019.10 (41708626..41730433)|
Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface. Localized to the apical glycocalyx surface.
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