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- Table of Contents
2 Citations 16 Q&As
6 Citations 11 Q&As
1 Citations 17 Q&As
1 Citations 15 Q&As
2 Citations 5 Q&As
1 Citations
Facts about Carcinoembryonic antigen-related cell adhesion molecule 5.
Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). .
| Human | |
|---|---|
| Gene Name: | CEACAM5 |
| Uniprot: | P06731 |
| Entrez: | 1048 |

| Belongs to: |
|---|
| immunoglobulin superfamily |

Carcinoembryonic antigen; carcinoembryonic antigen-related cell adhesion molecule 5; CD66e antigen; CD66e; CEA; CEACAM5; CEACAM-5; CEACD66e; DKFZp781M2392; Meconium antigen 100
Mass (kDA):
76.795 kDA

| Human | |
|---|---|
| Location: | 19q13.2 |
| Sequence: | 19; NC_000019.10 (41708626..41730433) |
Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface. Localized to the apical glycocalyx surface.




PMID: 3670312 by Beauchemin N., et al. Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen.
PMID: 3220478 by Barnett T., et al. Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.
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